M
M. Hewitson
Publications - 4
Citations - 980
M. Hewitson is an academic researcher. The author has contributed to research in topics: Genome & Throughput (business). The author has an hindex of 3, co-authored 3 publications receiving 950 citations.
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Journal ArticleDOI
Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans
Birte Sönnichsen,Liisa Koski,Andrew Walsh,P. Marschall,Beate Neumann,M. Brehm,Anne-Marie Alleaume,J. Artelt,Paulo Bettencourt,Etienne Cassin,M. Hewitson,C. Holz,Moddasar N. Khan,S. Lazik,Charles E. Martin,Björn Nitzsche,Martine Ruer,Joanne Stamford,Maria Winzi,R. Heinkel,Marion S. Röder,J. Finell,H. Häntsch,Steven J.M. Jones,Martin R. Jones,Martin R. Jones,Fabio Piano,Kristin C. Gunsalus,Karen Oegema,Pierre Gönczy,Pierre Gönczy,Alan Coulson,Alan Coulson,Anthony A. Hyman,Christophe Echeverri +34 more
TL;DR: This work used RNA-mediated interference to target 98% of all genes predicted in the C. elegans genome in combination with differential interference contrast time-lapse microscopy and developed a phenotypic profiling system, which shows high correlation with cellular processes and biochemical pathways, thus enabling to predict new functions for previously uncharacterized genes.
Full-genome RNAi profiling of early embryogenesis in Caenorhabditis
M. Hewitson,S. Lazik,Cecilie Martin,Joanne Stamford,R. Heinkel,Steven J.M. Jones,Martin R. Jones,Fabio Piano,Kristin C. Gunsalus,Karen Oegema,A. Coulson,Anthony A. Hyman,Christophe Echeverri,British Columbia +13 more
TL;DR: In this paper, the authors used RNA-mediated interference to target 98% of all genes predicted in the C. elegans genome in combination with differential interference contrast time-lapse microscopy.
OtherDOI
Exploring the Full Power of Combining High Throughput RNAi with High Content Readouts: From Target Discovery Screens to Drug Modifier Studies
Christoph Sachse,Cornelia Weiss‐Haljiti,Christian Holz,Kathrin Regener,Francoise Halley,Michael Hannus,Corina Frenzel,Sindy Kluge,M. Hewitson,Benjamin Bader,A Burd,Louise Perkins,Alexander A. Szewczak,Stefan Prechtl,Claudia Merz,Peter Rae,Dominik Mumberg,Christophe Echeverri +17 more