M
Moddasar N. Khan
Publications - 3
Citations - 987
Moddasar N. Khan is an academic researcher. The author has contributed to research in topics: Chemokine receptor & Chemokine. The author has an hindex of 2, co-authored 3 publications receiving 936 citations.
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Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans
Birte Sönnichsen,Liisa Koski,Andrew Walsh,P. Marschall,Beate Neumann,M. Brehm,Anne-Marie Alleaume,J. Artelt,Paulo Bettencourt,Etienne Cassin,M. Hewitson,C. Holz,Moddasar N. Khan,S. Lazik,Charles E. Martin,Björn Nitzsche,Martine Ruer,Joanne Stamford,Maria Winzi,R. Heinkel,Marion S. Röder,J. Finell,H. Häntsch,Steven J.M. Jones,Martin R. Jones,Martin R. Jones,Fabio Piano,Kristin C. Gunsalus,Karen Oegema,Pierre Gönczy,Pierre Gönczy,Alan Coulson,Alan Coulson,Anthony A. Hyman,Christophe Echeverri +34 more
TL;DR: This work used RNA-mediated interference to target 98% of all genes predicted in the C. elegans genome in combination with differential interference contrast time-lapse microscopy and developed a phenotypic profiling system, which shows high correlation with cellular processes and biochemical pathways, thus enabling to predict new functions for previously uncharacterized genes.
Journal ArticleDOI
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer
Chiara Berlato,Moddasar N. Khan,Tiziana Schioppa,Richard G. Thompson,Eleni Maniati,Anne Montfort,Maryam Jangani,Monica Canosa,Hagen Kulbe,Urs B. Hagemann,Alexander R. Duncan,Laura A. Fletcher,Robert W. Wilkinson,Thomas Powles,Sergio A. Quezada,Frances R. Balkwill +15 more
TL;DR: The anti-CCR4 antibody, alone or in combination with other immune modulators, is a potential treatment approach to human solid cancers with high levels of C CR4-expressing tumor-infiltrating leukocytes and abnormal plasma CCR4 ligand levels.