J
Joanne Stamford
Researcher at Max Planck Society
Publications - 4
Citations - 1200
Joanne Stamford is an academic researcher from Max Planck Society. The author has contributed to research in topics: Genome & Centrosome. The author has an hindex of 3, co-authored 4 publications receiving 1159 citations.
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Journal ArticleDOI
Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans
Birte Sönnichsen,Liisa Koski,Andrew Walsh,P. Marschall,Beate Neumann,M. Brehm,Anne-Marie Alleaume,J. Artelt,Paulo Bettencourt,Etienne Cassin,M. Hewitson,C. Holz,Moddasar N. Khan,S. Lazik,Charles E. Martin,Björn Nitzsche,Martine Ruer,Joanne Stamford,Maria Winzi,R. Heinkel,Marion S. Röder,J. Finell,H. Häntsch,Steven J.M. Jones,Martin R. Jones,Martin R. Jones,Fabio Piano,Kristin C. Gunsalus,Karen Oegema,Pierre Gönczy,Pierre Gönczy,Alan Coulson,Alan Coulson,Anthony A. Hyman,Christophe Echeverri +34 more
TL;DR: This work used RNA-mediated interference to target 98% of all genes predicted in the C. elegans genome in combination with differential interference contrast time-lapse microscopy and developed a phenotypic profiling system, which shows high correlation with cellular processes and biochemical pathways, thus enabling to predict new functions for previously uncharacterized genes.
Journal ArticleDOI
Identification and characterization of factors required for microtubule growth and nucleation in the early C. elegans embryo.
TL;DR: The findings suggest that fast microtubule growth is dependent on the amount of free tubulin and the ZYG-9-TAC-1 complex, and it is found that centrosomes do not nucleate MTs to saturation; rather, the depolymerizing kinesin-13 subfamily member KLP-7 is required to limit micro Tubulin outgrowth from centrosome.
Full-genome RNAi profiling of early embryogenesis in Caenorhabditis
M. Hewitson,S. Lazik,Cecilie Martin,Joanne Stamford,R. Heinkel,Steven J.M. Jones,Martin R. Jones,Fabio Piano,Kristin C. Gunsalus,Karen Oegema,A. Coulson,Anthony A. Hyman,Christophe Echeverri,British Columbia +13 more
TL;DR: In this paper, the authors used RNA-mediated interference to target 98% of all genes predicted in the C. elegans genome in combination with differential interference contrast time-lapse microscopy.
Supplemental Data Identification and Characterization of Factors Required for Microtubule Growth and Nucleation in the Early C. elegans Embryo
TL;DR: Depletion of the RanGAP homologue showed a slight but significant reduction in MT growth rate, and it was found that depletion of this homologue affected the growth rate of MTs.