M
Maja Theresa Dieterlen
Researcher at Leipzig University
Publications - 8
Citations - 512
Maja Theresa Dieterlen is an academic researcher from Leipzig University. The author has contributed to research in topics: Transplantation & P70-S6 Kinase 1. The author has an hindex of 5, co-authored 8 publications receiving 241 citations.
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Journal ArticleDOI
Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy : Second Consensus Report
Mercè Brunet,Teun van Gelder,Anders Åsberg,Vincent Haufroid,Vincent Haufroid,Dennis A. Hesselink,Loralie J. Langman,Florian Lemaitre,Pierre Marquet,Christoph Seger,Maria Shipkova,Alexander A. Vinks,Alexander A. Vinks,Pierre Wallemacq,Eberhard Wieland,Jean-Baptiste Woillard,Markus J. Barten,Klemens Budde,Helena Colom,Maja Theresa Dieterlen,Laure Elens,Kamisha L. Johnson-Davis,Paweł K. Kunicki,Iain MacPhee,Satohiro Masuda,Binu S. Mathew,Olga Millán,Tomoyuki Mizuno,Tomoyuki Mizuno,Dirk Jan A.R. Moes,Caroline Monchaud,Ofelia Noceti,Tomasz Pawinski,Nicolas Picard,Ron H.N. van Schaik,Claudia Sommerer,Nils Tore Vethe,Brenda C. M. de Winter,Uwe Christians,Stein Bergan +39 more
TL;DR: It is concluded that considerable advances in the different fields of tacrolimus monitoring have been achieved during this last decade, and the Expert Committee concludes that Continued efforts should focus on the opportunities to implement in clinical routine the combination of new standardized PK approaches with PG, and valid biomarkers to further personalize tacolimus therapy and to improve long-term outcomes for treated patients.
Journal ArticleDOI
Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology
Stein Bergan,Mercè Brunet,Dennis A. Hesselink,Kamisha L. Johnson-Davis,Paweł K. Kunicki,Florian Lemaitre,Pierre Marquet,Mariadelfina Molinaro,Ofelia Noceti,Smita Pattanaik,Tomasz Pawinski,Christoph Seger,Maria Shipkova,Jesse J. Swen,Teun van Gelder,Raman Venkataramanan,Eberhard Wieland,Jean-Baptiste Woillard,Tom C. Zwart,Markus J. Barten,Klemens Budde,Maja Theresa Dieterlen,Laure Elens,Vincent Haufroid,Satohiro Masuda,Olga Millán,Tomoyuki Mizuno,Tomoyuki Mizuno,Dirk Jan A.R. Moes,Michael Oellerich,Nicolas Picard,Linda Salzmann,Burkhard Tönshoff,Ron H.N. van Schaik,Nils Tore Vethe,Alexander A. Vinks,Pierre Wallemacq,Anders Åsberg,Loralie J. Langman +38 more
TL;DR: In this article, the status of personalized treatment with mycophenolic acid (MPA) is discussed, including the criteria for analytics, methods to estimate exposure including pharmacometrics, potential influence of pharmacogenetics, development of biomarkers, and the practical aspects of implementation of target concentration intervention.
Journal ArticleDOI
The chemokine SDF1 controls multiple steps of myogenesis through atypical PKCζ
TL;DR: It is found that SDF1 stimulates proliferation and induces migration of C2C12 cells with a potency similar to that of FGF2 and HGF, which both represent prototypical extracellular regulators of myogenesis.
Journal ArticleDOI
Durability and clinical experience using a bovine pericardial prosthetic aortic valve.
Sven Lehmann,Khalil Jawad,Maja Theresa Dieterlen,Alexandro Hoyer,Jens Garbade,Piroze M. Davierwala,Michael A. Borger +6 more
TL;DR: Outcomes from this large single-center cohort at increased surgical risk demonstrate excellent long-term durability of the Trifecta valve for SAVR and feasibility of treating SVD by V-in-V TAVI.
Journal ArticleDOI
Target Enzyme Activity and Phosphorylation of Pathway Molecules As Specific Biomarkers in Transplantation.
TL;DR: Clinical relevance of monitoring the activity of inosine-5′-monophosphate dehydrogenase (IMPDH), the target enzyme of mycophenolic acid, and of the phosphorylation of mechanistic target of rapamycin (mTOR) molecules is discussed.