M
Marcel G.J. Tilanus
Researcher at Maastricht University
Publications - 118
Citations - 3076
Marcel G.J. Tilanus is an academic researcher from Maastricht University. The author has contributed to research in topics: Human leukocyte antigen & Transplantation. The author has an hindex of 28, co-authored 116 publications receiving 2721 citations. Previous affiliations of Marcel G.J. Tilanus include Utrecht University & Maastricht University Medical Centre.
Papers
More filters
Journal ArticleDOI
An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas.
Paul Roepman,Lodewyk F. A. Wessels,Lodewyk F. A. Wessels,Nienke Kettelarij,Patrick Kemmeren,Antony J. Miles,Philip Lijnzaad,Marcel G.J. Tilanus,Ron Koole,G. J. Hordijk,Peter C. van der Vliet,Marcel J. T. Reinders,P.J. Slootweg,Frank C. P. Holstege +13 more
TL;DR: DNA microarray gene-expression profiling can detect lymph node metastases for primary head and neck squamous cell carcinomas that arise in the oral cavity and oropharynx and shows that the metastatic state can be deciphered from the primary tumor gene- expression pattern and that treatment can be substantially improved.
Journal ArticleDOI
Common and well-documented HLA alleles: 2012 update to the CWD catalogue.
Steven J. Mack,Pedro Cano,Jill A. Hollenbach,Jun He,Carolyn Katovich Hurley,Derek Middleton,M. E. Moraes,Shalini E. Pereira,Jane Kempenich,Elaine F. Reed,Michelle Setterholm,Anajane G. Smith,Marcel G.J. Tilanus,Margareth Torres,Michael D. Varney,Christien Voorter,Gottfried Fischer,Katharina Fleischhauer,Damian Goodridge,William Klitz,AM Little,Martin Maiers,Steven G.E. Marsh,Carlheinz Müller,Harriet Noreen,Erik H. Rozemuller,Alicia Sanchez-Mazas,David Senitzer,Elizabeth Trachtenberg,Marcelo Fernandez-Vina +29 more
TL;DR: The CWD catalogue will be updated on a regular basis moving forward, and will incorporate changes to the IMGT/HLA Database as well as empirical data from the histocompatibility and immunogenetics community.
Journal ArticleDOI
Functional characterization of the lectin pathway of complement in human serum.
Anja Roos,Lee H. Bouwman,Jeric R Munoz,Tahlita C M Zuiverloon,Maria C. Faber-Krol,Francien C Fallaux van den Houten,Ngaisah Klar-Mohamad,C. Erik Hack,Marcel G.J. Tilanus,Mohamed R. Daha +9 more
TL;DR: A novel functional assay is described that enables quantification of autologous complement activation via the LP in full human serum up to the formation of the membrane attack complex and offers novel possibilities for patient diagnostics as well as for the study of disease association with the LP.
Journal ArticleDOI
Follicular T helper cells and humoral reactivity in kidney transplant patients.
G. N. de Graav,Marjolein Dieterich,Dennis A. Hesselink,Karin Boer,M. C. Clahsen-van Groningen,Rens Kraaijeveld,Nicolle H.R. Litjens,Rachida Bouamar,Joris Vanderlocht,Marcel G.J. Tilanus,I. Houba,Andre Boonstra,Dave L. Roelen,Frans H.J. Claas,Michiel G. H. Betjes,Willem Weimar,Carla C. Baan +16 more
TL;DR: The data on T fh cells in kidney transplantation demonstrate that Tfh cells may mediate humoral alloreactivity, which is also seen in the immunosuppressed milieu.
Journal ArticleDOI
High-resolution HLA-DPB typing based upon computerized analysis of data obtained by fluorescent sequencing of the amplified polymorphic exon 2.
L.F. Versluis,Erik H. Rozemuller,Susan Tonks,Steven G.E. Marsh,Anne G.M. Bouwens,Julia G. Bodmer,Marcel G.J. Tilanus +6 more
TL;DR: A new DNA-based typing approach that is rapid, fully automated, and therefore suitable for routine typing, and easily applicable to other gene systems is developed.