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Marek Minarik

Researcher at Charles University in Prague

Publications -  95
Citations -  1860

Marek Minarik is an academic researcher from Charles University in Prague. The author has contributed to research in topics: Erlotinib & KRAS. The author has an hindex of 25, co-authored 90 publications receiving 1639 citations. Previous affiliations of Marek Minarik include Northeastern University & Massachusetts Institute of Technology.

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Toward Male Individualization with Rapidly Mutating Y‐Chromosomal Short Tandem Repeats

Kaye N. Ballantyne, +127 more
- 01 Aug 2014 - 
TL;DR: The value of RM Y‐STRs in identifying and separating unrelated and related males and providing a reference database is demonstrated and the value of Y‐ STRs relative to Yfiler is demonstrated.
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Evaluation of clinical relevance of examining K-ras, p16 and p53 mutations along with allelic losses at 9p and 18q in EUS-guided fine needle aspiration samples of patients with chronic pancreatitis and pancreatic cancer

TL;DR: EUS-guided FNA cytology combined with screening of K-ras mutations and allelic losses of tumor suppressors p16 and DPC4 represents a very sensitive approach in screening for pancreatic malignancy.
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Mutation-based detection and monitoring of cell-free tumor DNA in peripheral blood of cancer patients

TL;DR: Apart from conventional mutation detection approaches, several dedicated techniques have been presented to detect low levels of cfDNA in an excess of nontumorous (nonmutated) DNA, including real-time polymerase chain reaction (PCR), "BEAMing" (beads, emulsion, amplification, and magnetics), and denaturing capillary electrophoresis.
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Molecular biology of pancreatic cancer.

TL;DR: Understanding of the underlying molecular mechanisms should promote development of new methodology for early diagnosis and facilitate improvement in current approaches for pancreatic cancer treatment.
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Colorectal cancer screening: 20 years of development and recent progress

TL;DR: The Czech Republic is a typical example of a country with a long history of nationwide CRC screening programs in the face of very high CRC incidence and mortality rates, and switching to the option of a population-based program with personal invitation is currently being prepared.