M
Marguerite Ennis
Researcher at University of Toronto
Publications - 84
Citations - 6366
Marguerite Ennis is an academic researcher from University of Toronto. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 34, co-authored 75 publications receiving 5838 citations. Previous affiliations of Marguerite Ennis include University Health Network & Mount Sinai Hospital.
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Journal ArticleDOI
Metabolic factors, anthropometric measures, diet, and physical activity in long-term breast cancer survivors: change from diagnosis and comparison to non-breast cancer controls
TL;DR: The prevalence of the metabolic syndrome and diabetes/pre-diabetes was significantly higher in BC survivors than in controls group, notably in those with lower levels of physical activity.
Journal ArticleDOI
Effect of metformin versus placebo on metabolic factors in the MA.32 randomized breast cancer trial.
Pamela J. Goodwin,Ryan J. O. Dowling,Marguerite Ennis,Bingshu E. Chen,Wendy R. Parulekar,Lois E. Shepherd,Margot J. Burnell,Rachel Vander Meer,Andrea Molckovsky,Anagha Gurjal,Karen A. Gelmon,Jennifer A. Ligibel,Dawn L. Hershman,Ingrid A. Mayer,Timothy J. Whelan,Timothy J. Hobday,Priya Rastogi,Manuela Rabaglio-Poretti,Julie Lemieux,Alastair M. Thompson,Daniel Rea,Vuk Stambolic +21 more
TL;DR: In this article, the authors examined metformin impact on metabolic factors in non-diabetic subjects and determine whether this impact varies by baseline BMI, insulin, and rs11212617 SNP in CCTG MA.
Proceedings ArticleDOI
Abstract PD03-06: Clinical and Biologic Effects of Metformin in Early Stage Breast Cancer
Saroj Niraula,Vuk Stambolic,Rjo Dowling,Marguerite Ennis,Martin C. Chang,Susan J. Done,S Hallak,N Hood,Wey Liang Leong,Jaime Escallon,PJ Goodwin +10 more
TL;DR: A short term administration of metformin significantly reduced breast cancer cell proliferation (as measured by change in Ki67 index) and induced apoptosis (reflected by TUNEL) and was associated with improved insulin resistance.
Journal ArticleDOI
The prognostic effect of lipids on early-stage breast cancer (BC) outcome
Mala Bahl,Marguerite Ennis,Ian F. Tannock,Jan Hux,Kathleen I. Pritchard,Jarley Koo,Pamela J. Goodwin +6 more
TL;DR: A cohort of 535 women without known hyperlipidemia or diabetes, with stage T1-T3, N0-N1, M0 BC was assembled from July 1989 to June 1996, and total cholesterol (TC) and triglycerides (TG) were significantly correlated with age.
Journal ArticleDOI
Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 2: Approaches to Predict and Identify Late Recurrence, Research Directions.
Ryan J.O. Dowling,Ryan J.O. Dowling,Joseph A. Sparano,Pamela J. Goodwin,François-Clément Bidard,David W. Cescon,David W. Cescon,Sarat Chandarlapaty,Sarat Chandarlapaty,Joseph O. Deasy,Mitch Dowsett,Robert Gray,N. Lynn Henry,Funda Meric-Bernstam,Jane Perlmutter,George W. Sledge,Mangesh A. Thorat,Scott V. Bratman,Lisa A. Carey,Martin C. Chang,Angela DeMichele,Marguerite Ennis,Katarzyna J. Jerzak,Larissa A. Korde,Ana Elisa Lohmann,Eleftherios P. Mamounas,Wendy R. Parulekar,Meredith M. Regan,Daniel Schramek,Daniel Schramek,Vuk Stambolic,Vuk Stambolic,Timothy J. Whelan,Antonio C. Wolff,James R. Woodgett,Kevin Kalinsky,Daniel F. Hayes +36 more
TL;DR: Recent advances in disease detection and patient monitoring should be incorporated into novel clinical trials to evaluate approaches to enhance patient management and offer new options for effective late recurrence treatment and prevention strategies.