B
Bruno Millet
Researcher at University of Paris
Publications - 208
Citations - 5861
Bruno Millet is an academic researcher from University of Paris. The author has contributed to research in topics: Deep brain stimulation & Subthalamic nucleus. The author has an hindex of 41, co-authored 204 publications receiving 5321 citations. Previous affiliations of Bruno Millet include Paris Descartes University & University of Rennes.
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Journal ArticleDOI
Subthalamic nucleus stimulation in severe obsessive-compulsive disorder.
Luc Mallet,Mircea Polosan,Nematollah Jaafari,Nicolas Baup,Marie-Laure Welter,Denys Fontaine,Sophie Tezenas du Montcel,Jérôme Yelnik,Isabelle Chereau,Christophe Arbus,Sylvie Raoul,Bruno Aouizerate,Philippe Damier,Stephan Chabardes,Virginie Czernecki,Claire Ardouin,Marie-Odile Krebs,Eric Bardinet,Patrick Chaynes,Pierre Burbaud,Philippe Cornu,Philippe Derost,Thierry Bougerol,Benoit Bataille,Vianney Mattei,Didier Dormont,Bertrand Devaux,Marc Vérin,Jean-Luc Houeto,Pierre Pollak,Alim-Louis Benabid,Yves Agid,Paul Krack,Bruno Millet,Antoine Pelissolo,Non Renseigné +35 more
TL;DR: These preliminary findings suggest that stimulation of the subthalamic nucleus may reduce the symptoms of severe forms of OCD but is associated with a substantial risk of serious adverse events.
Journal ArticleDOI
Increased exonic de novo mutation rate in individuals with schizophrenia
Simon Girard,Julie Gauthier,Anne Noreau,Lan Xiong,Sirui Zhou,Loubna Jouan,Alexandre Dionne-Laporte,Dan Spiegelman,Edouard Henrion,Ousmane Diallo,Pascale Thibodeau,Isabelle Bachand,Jessie Y.J. Bao,Amy Hin Yan Tong,Chi-Ho Lin,Bruno Millet,Bruno Millet,Nematollah Jaafari,Nematollah Jaafari,Ridha Joober,Patrick A. Dion,Si Lok,Marie-Odile Krebs,Guy A. Rouleau,Guy A. Rouleau +24 more
TL;DR: This study sequenced the exomes of 14 schizophrenia probands and their parents to identify 15 de novo mutations (DNMs) in eight probands, which is significantly more than expected considering the previously reported DNM rate.
Journal ArticleDOI
Direct Measure of the De Novo Mutation Rate in Autism and Schizophrenia Cohorts
Philip Awadalla,Julie Gauthier,Rachel A. Myers,Rachel A. Myers,Ferran Casals,Fadi F. Hamdan,Alexander R. Griffing,Mélanie Côté,Edouard Henrion,Dan Spiegelman,Julien Tarabeux,Amélie Piton,Yan Yang,Adam R. Boyko,Carlos Bustamante,Lan Xiong,Judith L. Rapoport,Anjené M. Addington,J. Lynn E. DeLisi,Marie-Odile Krebs,Ridha Joober,Bruno Millet,Eric Fombonne,Laurent Mottron,Martine Zilversmit,Jon Keebler,Jon Keebler,Hussein Daoud,Claude Marineau,Marie-Hélène Roy-Gagnon,Marie-Pierre Dubé,Adam Eyre-Walker,Pierre Drapeau,Eric A. Stone,Ronald G. Lafrenière,Guy A. Rouleau +35 more
TL;DR: A direct measure of the de novo mutation rate and selective constraints from DNMs estimated from a deep resequencing data set generated from a large cohort of ASD and SCZ cases and population control individuals with available parental DNA is presented.
Journal ArticleDOI
Rare Mutations in N-methyl-D-aspartate Glutamate Receptors in Autism Spectrum Disorders and Schizophrenia
Julien Tarabeux,Julien Tarabeux,Julien Tarabeux,Oussama Kebir,Oussama Kebir,Julie Gauthier,Fadi F. Hamdan,Lan Xiong,Amélie Piton,Dan Spiegelman,Edouard Henrion,Bruno Millet,Ferid Fathalli,Ridha Joober,Judith L. Rapoport,Lynn E. DeLisi,Eric Fombonne,Laurent Mottron,Nadine Forget-Dubois,Michel Boivin,Jacques L. Michaud,Pierre Drapeau,Ronald G. Lafrenière,Guy A. Rouleau,Marie-Odile Krebs,Marie-Odile Krebs +25 more
TL;DR: The present results support the hypothesis that rare de novo mutations in GRIN2A or GRin2B can be associated with cases of sporadic SCZ or ASD, just as it has recently been described for the related neurodevelopmental disease intellectual disability.
Journal ArticleDOI
Does subthalamic nucleus stimulation induce apathy in Parkinson's disease?
Dominique Drapier,Sophie Drapier,Paul Sauleau,Claire Haegelen,Sylvie Raoul,Isabelle Biseul,Julie Anne Peron,François Lallement,Isabelle Rivier,Jean-Michel Reymann,Gilles Edan,Marc Vérin,Bruno Millet +12 more
TL;DR: Although STN-DBS constitutes a therapeutic advance for severely disabled patients with Parkinson’s disease, this surgical procedure may contribute to the inducing of apathy, which raises the issue of the direct influence of STn- DBS on the limbic system by diffusion of stimulus to the medial limbic compartment of STN.