Marie S. Isidor

TL;DR: Results show that GLP-1R agonists have potential therapeutic potential in the treatment of obstructive pulmonary diseases, such as chronic obstructive lung disease, by decreasing the severity of acute exacerbations.

TL;DR: It is suggested that upregulation of MCT1- and MCT4-mediated lactate flux capacity and NBCe1-mediated HCO3−/pH homeostasis are important for the physiological function of mature adipocytes.

TL;DR: UCP1 expression is differently affected by ATRA in mouse and human adipocyte cell lines, whereas expression of UCP1 in human adipocytes is not increased by exposure to ATRA.

TL;DR: Brown adipocytes rely on glucose consumption and glycolytic flux to achieve maximum thermogenic output, with Glycolysis likely supporting thermogenesis not only by pyruvate formation but also by supplying intermediates for efferent metabolic pathways.

TL;DR: In this paper, the N terminus of GPR3 confers intrinsic signaling activity, resulting in continuous Gs-coupling and cAMP production without an exogenous ligand.