M
Martina Casenghi
Researcher at Médecins Sans Frontières
Publications - 16
Citations - 1144
Martina Casenghi is an academic researcher from Médecins Sans Frontières. The author has contributed to research in topics: Tuberculosis & Medicine. The author has an hindex of 8, co-authored 11 publications receiving 930 citations.
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Journal ArticleDOI
Evaluation of Tuberculosis Diagnostics in Children: 1. Proposed Clinical Case Definitions for Classification of Intrathoracic Tuberculosis Disease. Consensus From an Expert Panel
Stephen M. Graham,Stephen M. Graham,Tahmeed Ahmed,Farhana Amanullah,Renee Browning,Vicky Cárdenas,Martina Casenghi,Luis E. Cuevas,Marianne Gale,Robert P. Gie,M. Grzemska,Ed Handelsman,Mark Hatherill,Anneke C. Hesseling,Patrick Jean-Philippe,Beate Kampmann,Beate Kampmann,Sushil K. Kabra,Christian Lienhardt,Jennifer Lighter-Fisher,Shabir A. Madhi,Mamodikoe Makhene,Ben J. Marais,David F. McNeeley,Heather J. Menzies,Charles D. Mitchell,Surbhi Modi,Lynne M. Mofenson,Philippa Musoke,Sharon Nachman,Clydette Powell,Mona Rigaud,Vanessa Rouzier,Jeffrey R. Starke,Soumya Swaminathan,Claire Wingfield +35 more
TL;DR: The definitions presented in this article are intended for use in clinical research to evaluate diagnostic assays and not for individual patient diagnosis or treatment decisions.
Journal ArticleDOI
Clinical Case Definitions for Classification of Intrathoracic Tuberculosis in Children: An Update
Stephen M. Graham,Stephen M. Graham,Stephen M. Graham,Luis E. Cuevas,Patrick Jean-Philippe,Renee Browning,Martina Casenghi,Anne Detjen,Devasena Gnanashanmugam,Anneke C. Hesseling,Beate Kampmann,Anna M. Mandalakas,Ben J. Marais,Marco Schito,Hans M. L. Spiegel,Jeffrey R. Starke,Carol Worrell,Heather J. Zar +17 more
TL;DR: The updated case definitions proposed here incorporate a number of key changes that aim to reduce complexity and improve research performance, while maintaining the original focus on symptomatic children suspected of having intrathoracic tuberculosis.
Journal ArticleDOI
Tuberculosis Diagnostics and Biomarkers: Needs, Challenges, Recent Advances, and Opportunities
Ruth McNerney,Markus Maeurer,Ibrahim Abubakar,Ibrahim Abubakar,Ben J. Marais,Timothy D. McHugh,Nathan Ford,Karin Weyer,Steve Lawn,Steve Lawn,Martin P. Grobusch,Ziad A. Memish,S. Bertel Squire,Giuseppe Pantaleo,Jeremiah Chakaya,Martina Casenghi,Giovanni Batista Migliori,Peter Mwaba,Lynn S. Zijenah,Michael Hoelscher,Helen Cox,Helen Cox,Soumya Swaminathan,Peter S. Kim,Marco Schito,Marco Schito,Alexandre Harari,Matthew Bates,Matthew Bates,Samana Schwank,Justin O'Grady,Michel Pletschette,Lucica Ditui,Rifat Atun,Alimuddin Zumla +34 more
TL;DR: This review highlights unanswered questions, challenges, recent advances, unresolved operational and technical issues, needs, and opportunities related to tuberculosis diagnostics.
Journal ArticleDOI
Defining the Needs for Next Generation Assays for Tuberculosis
Claudia M. Denkinger,Sandra V. Kik,Daniela Maria Cirillo,Martina Casenghi,Thomas M. Shinnick,Karin Weyer,Chris Gilpin,Catharina Boehme,Marco Schito,Michael E. Kimerling,Madhukar Pai +10 more
TL;DR: The developed target product profiles, along with complimentary work presented in this supplement, will help to facilitate the interaction between the tuberculosis community and the diagnostics industry with the goal to lead the way toward the post-2015 global tuberculosis targets.
Journal ArticleDOI
Evaluation of Tuberculosis Diagnostics in Children: 2. Methodological Issues for Conducting and Reporting Research Evaluations of Tuberculosis Diagnostics for Intrathoracic Tuberculosis in Children. Consensus From an Expert Panel
Luis E. Cuevas,Renee Browning,Patrick M.M. Bossuyt,Martina Casenghi,Mark F. Cotton,Andrea T. Cruz,Lori E. Dodd,Francis Drobniewski,Marianne Gale,Stephen M. Graham,M. Grzemska,Norbert Heinrich,Anneke C. Hesseling,Robin Huebner,Patrick Jean-Philippe,Sushil K. Kabra,Beate Kampmann,Beate Kampmann,Deborah A. Lewinsohn,Meijuan Li,Christian Lienhardt,Anna M. Mandalakas,Ben J. Marais,Heather J. Menzies,Grace Montepiedra,Charles Mwansambo,Richard A. Oberhelman,Paul Palumbo,Estelle Russek-Cohen,David Shapiro,Betsy Smith,Giselle Soto-Castellares,Jeffrey R. Starke,Soumya Swaminathan,Claire Wingfield,Carol Worrell +35 more
TL;DR: This consensus statement is an important step toward ensuring greater rigor and comparability of pediatric tuberculosis diagnostic research, with the aim of realizing the full potential of better tests for children.