M
Michael E. Wechsler
Researcher at National Jewish Health
Publications - 9
Citations - 385
Michael E. Wechsler is an academic researcher from National Jewish Health. The author has contributed to research in topics: Five prime untranslated region & Microbiome. The author has an hindex of 6, co-authored 9 publications receiving 272 citations. Previous affiliations of Michael E. Wechsler include Jewish Hospital.
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Journal ArticleDOI
Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment
Juliana Durack,Susan V. Lynch,Snehal Nariya,Nirav R. Bhakta,Avraham Beigelman,Mario Castro,Anne Marie Dyer,Elliot Israel,Monica Kraft,Richard J. Martin,David T. Mauger,Sharon R. Rosenberg,Tonya Sharp-King,Steven R. White,Prescott G. Woodruff,Pedro C. Avila,Loren C. Denlinger,Fernando Holguin,Stephen C. Lazarus,Njira L Lugogo,Wendy C. Moore,Stephen P. Peters,Loretta G. Que,Lewis J. Smith,Christine A. Sorkness,Michael E. Wechsler,Sally E. Wenzel,Homer A. Boushey,Yvonne J. Huang +28 more
TL;DR: Even in subjects with mild steroid‐naive asthma, differences in the bronchial microbiome are associated with immunologic and clinical features of the disease, suggesting possible microbiome targets for future approaches to asthma treatment or prevention.
Journal ArticleDOI
Bacterial biogeography of adult airways in atopic asthma.
Juliana Durack,Yvonne J. Huang,Snehal Nariya,Laura S. Christian,K. Mark Ansel,Avraham Beigelman,Mario Castro,Anne-Marie Dyer,Elliot Israel,Monica Kraft,Richard J. Martin,David T. Mauger,Sharon R. Rosenberg,Tonya S. King,Steven R. White,Loren C. Denlinger,Fernando Holguin,Stephen C. Lazarus,Njira L Lugogo,Stephen P. Peters,Lewis J. Smith,Michael E. Wechsler,Susan V. Lynch,Homer A. Boushey +23 more
TL;DR: Induced sputum is superior to nasal brush or oral wash for assessing bronchial microbiota composition in asthmatic adults, and the microbiota in induced spUTum are distinct, reflecting enrichment of oral bacteria.
Journal ArticleDOI
Impact of Age and Sex on Response to Asthma Therapy
Ryan M. Dunn,Erik Lehman,Vernon M. Chinchilli,Richard J. Martin,Homer A. Boushey,Elliot Israel,Monica Kraft,Stephen C. Lazarus,Robert F. Lemanske,Njira L Lugogo,Stephen P. Peters,Christine A. Sorkness,Stanley J. Szefler,Michael E. Wechsler +13 more
TL;DR: Older age is associated with an increased risk of treatment failure, particularly in subjects taking inhaled corticosteroids, and females had a slightly higher FEV1 % predicted than males but similar asthma control measures.
Journal ArticleDOI
The Placebo Effect in Asthma
TL;DR: This paper will review current literature on placebos in general and specifically on the placebo response in asthma, focusing on what the authors know about the mechanisms behind the placebo effect, whether there is a specific portion of the population who responds to placebos, which patient outcomes are influenced by the Placebo effect, and whether the effect can be augmented.
Iconography : The effects of an insertion in the 5′UTR of the AMCase on gene expression and pulmonary functions
Esra Birben,Cansin Sackesen,Shamsah Kazani,Gizem Tincer,Cagatay Karaaslan,Berna Durgunsu,Ihsan Gursel,Michael E. Wechsler,Elliot Israel,Ömer Kalayci +9 more
TL;DR: This study shows that a ten base pair insertion in the 5'UTR region of AMCase gene may modify gene expression and thus may affect the severity of asthma, however, its effects appear to be different in different populations.