M
Michael Q. Zhang
Researcher at Tsinghua University
Publications - 396
Citations - 46412
Michael Q. Zhang is an academic researcher from Tsinghua University. The author has contributed to research in topics: Gene & Chromatin. The author has an hindex of 93, co-authored 378 publications receiving 42008 citations. Previous affiliations of Michael Q. Zhang include Chinese Academy of Sciences & Peking Union Medical College Hospital.
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RNA Secondary Structure Prediction
TL;DR: This chapter contains sections titled: Introduction, Basic Definitions, Combinatorial Algorithm, Energy Minimization Algorithms, Phylogenetic Comparative Methods, Stochastic Context-Free Grammar Method, Conclusions, References.
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Deciphering hierarchical organization of topologically associated domains through change-point testing.
TL;DR: HiCKey as discussed by the authors uses a generalized likelihood-ratio (GLR) test for detecting change-points in an interaction matrix that follows a negative binomial distribution or general mixture distribution, and then employs several optimal search strategies to decipher hierarchical TADs with p values calculated by the GLR test.
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Identifying the 3'-terminal exon in human DNA.
TL;DR: JTEF is a new program for finding 3' terminal exons in human DNA sequences based on quadratic discriminant analysis, a standard non-linear statistical pattern recognition method that will become a valuable tool for genome annotation and gene functional studies.
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ModuleRole: A tool for modulization, role determination and visualization in protein-protein interaction networks
Guipeng Li,Ming Li,Yi Wei Zhang,Dong Wang,Rong Li,Rong Li,Roger Guimerà,Juntao Tony Gao,Michael Q. Zhang,Michael Q. Zhang +9 more
TL;DR: ModuleRole is a user-friendly web server tool which finds modules in PPI network and defines the roles for every node, and produces files for visualization in Cytoscape and Pajek, the first program which provides interactive and very friendly interface for biologists to find and visualize modules and roles of proteins in P PI network.
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A Bayesian Method for Disentangling Dependent Structure of Epistatic Interaction
TL;DR: RBP is a powerful method to infer detailed dependence structures in epistatic interactions and is consistent with the current knowledge of haplotype effect of these two genes on T1D.