M
Michihiko Ito
Researcher at Kitasato University
Publications - 85
Citations - 3394
Michihiko Ito is an academic researcher from Kitasato University. The author has contributed to research in topics: Gene & Xenopus. The author has an hindex of 26, co-authored 78 publications receiving 2984 citations. Previous affiliations of Michihiko Ito include University of Tokyo & Laboratory of Molecular Biology.
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Journal ArticleDOI
Genome evolution in the allotetraploid frog Xenopus laevis
Adam M. Session,Adam M. Session,Yoshinobu Uno,Taejoon Kwon,Taejoon Kwon,Jarrod Chapman,Atsushi Toyoda,Shuji Takahashi,Akimasa Fukui,Akira Hikosaka,Atsushi Suzuki,Mariko Kondo,Simon J. van Heeringen,Ian K. Quigley,Sven Heinz,Hajime Ogino,Haruki Ochi,Uffe Hellsten,Jessica B. Lyons,Oleg Simakov,Nicholas H. Putnam,Jonathan C. Stites,Yoko Kuroki,Toshiaki Tanaka,Tatsuo Michiue,Minoru Watanabe,Ozren Bogdanovic,Ryan Lister,Georgios Georgiou,Sarita S. Paranjpe,Ila van Kruijsbergen,Shengquiang Shu,Joseph W. Carlson,Tsutomu Kinoshita,Yuko Ohta,Shuuji Mawaribuchi,Jerry Jenkins,Jane Grimwood,Jeremy Schmutz,Therese Mitros,Sahar V. Mozaffari,Yutaka Suzuki,Yoshikazu Haramoto,Takamasa S. Yamamoto,Chiyo Takagi,Rebecca Heald,Kelly E. Miller,Christian D. Haudenschild,Jacob O. Kitzman,Takuya Nakayama,Yumi Izutsu,Jacques Robert,Joshua D. Fortriede,Kevin A. Burns,Vaneet Lotay,Kamran Karimi,Yuuri Yasuoka,Darwin S. Dichmann,Martin F. Flajnik,Douglas W. Houston,Jay Shendure,Louis DuPasquier,Peter D. Vize,Aaron M. Zorn,Michihiko Ito,Edward M. Marcotte,John B. Wallingford,Yuzuru Ito,Makoto Asashima,Naoto Ueno,Naoto Ueno,Yoichi Matsuda,Gert Jan C. Veenstra,Asao Fujiyama,Asao Fujiyama,Asao Fujiyama,Richard M. Harland,Masanori Taira,Daniel S. Rokhsar,Daniel S. Rokhsar,Daniel S. Rokhsar +80 more
TL;DR: The Xenopus laevis genome is sequenced and it is estimated that the two diploid progenitor species diverged around 34 million years ago and combined to form an allotetraploid around 17–18 Ma, where more than 56% of all genes were retained in two homoeologous copies.
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A W-linked DM-domain gene, DM-W, participates in primary ovary development in Xenopus laevis.
Shin Yoshimoto,Ema Okada,Hirohito Umemoto,Kei Tamura,Yoshinobu Uno,Chizuko Nishida-Umehara,Yoichi Matsuda,Nobuhiko Takamatsu,Tadayoshi Shiba,Michihiko Ito +9 more
TL;DR: Results suggest that DM-W is a likely sex (ovary)-determining gene in X. laevis and obtained molecular evidence of a W-chromosome in this species.
Journal ArticleDOI
JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a scaffold factor in the JNK signaling pathway
Michihiko Ito,Katsuji Yoshioka,Mizuho Akechi,Shinya Yamashita,Nobuhiko Takamatsu,Kenji Sugiyama,Masahiko Hibi,Yusaku Nakabeppu,Tadayoshi Shiba,Ken-ichi Yamamoto +9 more
TL;DR: Results suggest that JSAP1 functions as a scaffold protein in the JNK3 cascade, and discuss a scaffolding role for JSAP 1 in theJNK1 and JNK2 cascades.
Journal ArticleDOI
Determinations of the DNA sequence of the mreB gene and of the gene products of the mre region that function in formation of the rod shape of Escherichia coli cells.
M. Doi,Masaaki Wachi,Fumitoshi Ishino,Shigeo Tomioka,Michihiko Ito,Y Sakagami,A Suzuki,Michio Matsuhashi +7 more
TL;DR: The 6.5-kilobase mre region at 71 min in the Escherichia coli chromosome map, where genes involved in formation of a rod-shaped cell form a gene cluster, was analyzed by in vivo protein synthesis in a maxicell system and by base sequencing of DNA.
Journal ArticleDOI
Opposite roles of DMRT1 and its W-linked paralogue, DM-W, in sexual dimorphism of Xenopus laevis: implications of a ZZ/ZW-type sex-determining system
TL;DR: A novel model for a ZZ/ZW-type system in which DM-W directs female sex as a sex-determining gene, by antagonizing DMRT1 is supported, and it is suggested thatDM-W diverged from D MRT1 as a dominant-negative type gene, i.e. as a `neofunctionalization' gene for the ZZ /ZW/type system.