M
Mohamed Jaber
Researcher at University of Bordeaux
Publications - 31
Citations - 9089
Mohamed Jaber is an academic researcher from University of Bordeaux. The author has contributed to research in topics: Dopamine & Dopaminergic. The author has an hindex of 18, co-authored 23 publications receiving 8659 citations. Previous affiliations of Mohamed Jaber include Howard Hughes Medical Institute & Duke University.
Papers
More filters
Journal ArticleDOI
Dopamine Receptors: From Structure to Function
TL;DR: Target deletion of several of these dopamine receptor genes in mice should provide valuable information about their physiological functions and provide unequivocal evidence for the involvement of one of these receptors in the etiology of various central nervous system disorders.
Journal ArticleDOI
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
TL;DR: In homozygote mice, dopamine persists at least 100 times longer in the extracellular space, explaining the biochemical basis of the hyperdopaminergic phenotype and demonstrating the critical role of the transporter in regulating neurotransmission.
Journal ArticleDOI
Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity.
Raul R. Gainetdinov,William C. Wetsel,Sara R. Jones,Edward D. Levin,Mohamed Jaber,Marc G. Caron +5 more
TL;DR: The parallels between the DAT knockout mice and individuals with ADHD suggest that common mechanisms may underlie some of their behaviors and responses to psychostimulants.
Journal ArticleDOI
Dopamine receptors and brain function.
TL;DR: The recent characterization of D3 and D4 receptors which are, interestingly, expressed in areas of the CNS mediating cognition and affect or showing increased affinity for certain neuroleptics, have renewed the interest and hope of finding effective neurolePTics devoid of side effects.
Journal ArticleDOI
Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function.
Mohamed Jaber,Walter J. Koch,Howard A. Rockman,Bradley R. Smith,Richard A. Bond,Kathleen K. Sulik,John Ross,Robert J. Lefkowitz,Marc G. Caron,Bruno Giros,Bruno Giros +10 more
TL;DR: It is demonstrated that beta ARK1 appears to be the predominant GRK in early embryogenesis and that it plays a fundamental role in cardiac development.