M
Murray J. Cairns
Researcher at University of Newcastle
Publications - 201
Citations - 14007
Murray J. Cairns is an academic researcher from University of Newcastle. The author has contributed to research in topics: microRNA & Gene. The author has an hindex of 45, co-authored 175 publications receiving 10172 citations. Previous affiliations of Murray J. Cairns include Harvard University & Johnson & Johnson.
Papers
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Journal ArticleDOI
Cell type-specific manifestations of cortical thickness heterogeneity in schizophrenia
Maria A Di Biase,Michael P Geaghan,William R. Reay,Jakob Seidlitz,Cynthia Shannon Weickert,Alice Pébay,Melissa J. Green,Yann Quidé,Joshua R. Atkins,Michael J. Coleman,Sylvain Bouix,Evdokiya Knyazhanskaya,Amanda E. Lyall,Ofer Pasternak,Marek Kubicki,Yogesh Rathi,Andrew Visco,Megan Gaunnac,Jinglei Lv,Raquelle I. Mesholam-Gately,Kathryn E. Lewandowski,Daphne J. Holt,Matcheri S. Keshavan,Christos Pantelis,Dost Öngür,Alan Breier,Murray J. Cairns,Martha E. Shenton,Andrew Zalesky +28 more
TL;DR: In this paper , the authors sought to determine whether cortical thickness heterogeneity in schizophrenia relates to interregional variation in distinct neural cell types, as inferred from established gene expression data and person-specific genomic variation.
Journal ArticleDOI
Alteration of miRNA-mRNA interactions in lymphocytes of individuals with schizophrenia
Michael P Geaghan,Joshua R. Atkins,Alan M. Brichta,Paul A. Tooney,Rodney J. Scott,Vaughan J. Carr,Murray J. Cairns +6 more
TL;DR: Interestingly, while the authors explored expression in lymphocytes, the systems biology of miRNA-mRNA interactions was suggestive of significant pleiotropy with enrichment of networks related to neuronal activity, with males showing significantly more differentially expressed genes.
Journal ArticleDOI
The effect of a muscarinic receptor 1 gene variant on grey matter volume in schizophrenia
Vanessa Cropley,Elizabeth Scarr,Elizabeth Scarr,Alex Fornito,Alex Fornito,Paul Klauser,Paul Klauser,Chad A. Bousman,Chad A. Bousman,Rodney J. Scott,Murray J. Cairns,Paul A. Tooney,Christos Pantelis,Christos Pantelis,Brian Dean,Brian Dean +15 more
TL;DR: Preliminary results suggest that the rs2067477 genotype is associated with brain structure in the right precentral gyrus in individuals with schizophrenia/schizoaffective disorder.
Journal ArticleDOI
Dysregulation of circRNA expression in the peripheral blood of individuals with schizophrenia and bipolar disorder.
TL;DR: In this article, the authors provided a comprehensive analysis of circRNA expression in peripheral blood mononuclear cells (PBMCs) from 39 patients with schizophrenia and bipolar disorder as well as 20 healthy individuals using deep RNA-seq.
Patent
Zymogenic nucleic acid detection methods, and related molecules and kits
TL;DR: In this paper, a method for detecting and quantitatively determining a target nucleic acid sequence in a sample, which comprises contacting the sample with a primer and a zymogene which encodes, but which itself is the anti-sense sequence of, a catalytic nucleic acids sequence, is presented.