scispace - formally typeset
M

Murray J. Cairns

Researcher at University of Newcastle

Publications -  201
Citations -  14007

Murray J. Cairns is an academic researcher from University of Newcastle. The author has contributed to research in topics: microRNA & Gene. The author has an hindex of 45, co-authored 175 publications receiving 10172 citations. Previous affiliations of Murray J. Cairns include Harvard University & Johnson & Johnson.

Papers
More filters
Posted ContentDOI

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects: CNV Analysis Group and the Schizophrenia Working Group of the Psychiatric Genomics Consortium

Christian R. Marshall, +343 more
- 23 Feb 2016 - 
TL;DR: In this article, a centralized analysis pipeline was applied to a SCZ cohort of 21,094 cases and 20,227 controls and the authors observed a global enrichment of CNV burden in cases (OR=1.11, P=5.7e −15 ), which persisted after excluding loci implicated in previous studies.
Journal ArticleDOI

Circulating miRNA Biomarkers for Schizophrenia

TL;DR: The elevated levels of circulating serum microRNA (miRNA) levels were shown to be relatively specific to schizophrenia, as no significant difference was observed between 400 control subjects and 162 subjects with nonschizophrenia psychiatric disorders, including major depression, anxiety, bipolar disorder, and other atypical psychiatric diseases.
Patent

Zymogenic nucleic acid detection method, and related olecules and kits

TL;DR: In this paper, a method for detecting and quantitatively determining a target nucleic acid sequence in a sample, which comprises contacting the sample with a primer and a zymogene which encodes, but which itself is the anti-sense sequence of, a catalytic nucleic acids sequence, is presented.
Journal ArticleDOI

The DNA sequence specificity of hedamycin damage determined by ligation-mediated PCR and linear amplification.

TL;DR: In this article, the DNA sequence specificity of hedamycin damage was compared using two techniques: Ligation-mediated PCR (LMPCR) and Linear Amplification (LA).
Journal ArticleDOI

Comparison of the sequence specificity of cis-diamminedichloroplatinum (II) damage in guanine- and 7-deazaguanine-containing DNA

TL;DR: Results indicate that the N7 of guanine is not required in the formation of some cisplatin adducts, which would indicate that DNA polymerase blocking lesions formed at relatively weak sites are not required.