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Murray J. Cairns

Researcher at University of Newcastle

Publications -  201
Citations -  14007

Murray J. Cairns is an academic researcher from University of Newcastle. The author has contributed to research in topics: microRNA & Gene. The author has an hindex of 45, co-authored 175 publications receiving 10172 citations. Previous affiliations of Murray J. Cairns include Harvard University & Johnson & Johnson.

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Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept

Barbara Franke, +562 more
TL;DR: In this article, the authors integrated results from common variant studies of schizophrenia (33,636 cases, 43,008 controls) and volumes of several (mainly subcortical) brain structures (11,840 subjects).
Book ChapterDOI

Target-site selection for the 10-23 DNAzyme.

TL;DR: A multiplex assay was developed for simultaneous comparative analysis of 50 or more different DNAzymes in one reaction to optimise the process of target-site selection in long RNA substrates, and may be applicable to locating accessible sites for other nucleic acid-based gene suppression strategies.
Journal ArticleDOI

The MIR137 VNTR rs58335419 Is Associated With Cognitive Impairment in Schizophrenia and Altered Cortical Morphology.

TL;DR: It is observed that the MIR137 4-repeats VNTR (VNTR4) variant was enriched in a cognitive deficit subtype of schizophrenia and associated with altered brain morphology, including thicker left inferior temporal gyrus and deeper right postcentral sulcus.
Journal ArticleDOI

Germ cell-specific sustained activation of Wnt signalling perturbs spermatogenesis in aged mice, possibly through non-coding RNAs.

TL;DR: This study confirmed the activity of Wnt signalling in mouse, dog and human testes, and confirmed upregulation of this unique non-coding RNA in mutant testis.