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Nancy A. Jenkins
Researcher at Houston Methodist Hospital
Publications - 743
Citations - 105243
Nancy A. Jenkins is an academic researcher from Houston Methodist Hospital. The author has contributed to research in topics: Gene & Gene mapping. The author has an hindex of 155, co-authored 741 publications receiving 101587 citations. Previous affiliations of Nancy A. Jenkins include Institute of Molecular and Cell Biology & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
Genomic mapping of murine Zp-2 and Zp-3, two oocyte-specific loci encoding zona pellucida proteins.
R. D. Lunsford,Nancy A. Jenkins,Christine A. Kozak,Li-Fang Liang,C. M. Silan,Neal G. Copeland,Jurrien Dean +6 more
TL;DR: Using DNA isolated from hamster-mouse somatic cell hybrids and from C57BL/6J X Mus spretus interspecific backcross progeny, zp-2 was located on chromosome 7, 11.3 +/- 3.2 cM distal to Tyr, and Zp-3 was Located on chromosome 5, 9.2 +/- 2.9 cMdistal to Gus.
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A comprehensive SNP-based genetic analysis of inbred mouse strains
Shirley Tsang,Zhonghe Sun,Brian T. Luke,Claudia Stewart,Nicole Lum,Melissa Gregory,Xiaolin Wu,Marianne Subleski,Nancy A. Jenkins,Neal G. Copeland,David J. Munroe +10 more
TL;DR: The mapping and genotyping of 673 SNPs in 55 of the most commonly used mouse strains have allowed us to construct a phylogenetic tree that correlates and expands known genealogical relationships and clarifies the origin of strains previously having an uncertain ancestry.
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Provirus insertion in Tpl-1, an Ets-1-related oncogene, is associated with tumor progression in Moloney murine leukemia virus-induced rat thymic lymphomas.
Susan E. Bear,Alfonso Bellacosa,Pedro A. Lazo,Nancy A. Jenkins,Neal G. Copeland,Charles Hanson,Goran Levan,Philip N. Tsichlis +7 more
TL;DR: Analysis of Tpl-1 cDNA clones revealed that the two are closely related, and a rearrangement in this region in the primary tumor derived from the thymus of one animal but not in a clone of the same tumor segregating in the spleen was revealed.
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The Orphan Nuclear Receptor RORα (RORA) Maps to a Conserved Region of Homology on Human Chromosome 15q21-q22 and Mouse Chromosome 9
TL;DR: The human RORA gene is mapped by fluorescence in situ hybridization to human chromosome 15q21-q22, which places the human R ORA gene in the proximity of the PML gene, which is involved in a reciprocal chromosomal translocation t(15:17) with the RARA gene in patients with acute promyelocytic leukemia.
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Coordinated transcriptional regulation of bone homeostasis by Ebf1 and Zfp521 in both mesenchymal and hematopoietic lineages
Riku Kiviranta,Kei Yamana,Hiroaki Saito,Daniel K. Ho,Julius Laine,Kati Tarkkonen,Vappu Nieminen-Pihala,Eric Hesse,Diego Correa,Jorma A. Määttä,Lino Tessarollo,Evan D. Rosen,William C. Horne,Nancy A. Jenkins,Neal G. Copeland,Søren Warming,Roland Baron +16 more
TL;DR: Absence of the transcriptional regulator Zfp521 results in decreased bone formation by osteoblasts and increased osteoclast differentiation, largely via ZFP521’s regulation ofThe transcription factor Ebf1.