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Nancy A. Jenkins
Researcher at Houston Methodist Hospital
Publications - 743
Citations - 105243
Nancy A. Jenkins is an academic researcher from Houston Methodist Hospital. The author has contributed to research in topics: Gene & Gene mapping. The author has an hindex of 155, co-authored 741 publications receiving 101587 citations. Previous affiliations of Nancy A. Jenkins include Institute of Molecular and Cell Biology & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
The Gene for a Variant Form of the Polyadenylation Protein CstF-64 Is on Chromosome 19 and Is Expressed in Pachytene Spermatocytes in Mice
Brinda Dass,K. Wyatt McMahon,Nancy A. Jenkins,Debra J. Gilbert,Neal G. Copeland,Clinton C. MacDonald +5 more
TL;DR: The cloning and characterization of the mouse τCstF-64 cDNA is described, which maps to chromosome 19, which fits the criteria of the variant Cstf-64, including antibody reactivity, size, germ cell expression, and a common proteolytic digest pattern with τCStF- 64 from testis.
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Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma.
Takahiro Kodama,Justin Y. Newberg,Michiko Kodama,Roberto Rangel,Kosuke Yoshihara,Jean C. Tien,Pamela H. Parsons,Hao Wu,Milton J. Finegold,Neal G. Copeland,Nancy A. Jenkins +10 more
TL;DR: It is shown that mobilization of Sleeping Beauty transposons in immortalized mouse hepatoblasts induces mesenchymal liver tumors on transplantation to nude mice, and deregulation of these genes in human HCC was found to confer sorafenib resistance through apoptotic tolerance and reduced proliferation, consistent with recent studies showing that EMT contributes to the chemoresistance of tumor cells.
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Chromosomal localization of a gene, GFI1, encoding a novel zinc finger protein reveals a new syntenic region between man and rodents
Daphne W. Bell,Takahiro Taguchi,Nancy A. Jenkins,Debra J. Gilbert,Neal G. Copeland,C. B. Gilks,P A Zweidler-Mckay,H L Grimes,Philip N. Tsichlis,Joseph R. Testa +9 more
TL;DR: Comparative mapping data presented here describes a new syntenic region between man and rodents that is involved in transcriptional regulation and binding to DNA.
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Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21.
Ivan Bergstein,Leonard M. Eisenberg,Jayant Bhalerao,Nancy A. Jenkins,Neal G. Copeland,Michael P. Osborne,Anne M. Bowcock,Anthony M. C. Brown +7 more
TL;DR: It is shown that human WNT14 maps to chromosome 1 and that WNT15 maps distal to BRCA1 on chromosome 17q21, where it lies within 125 kb of another WNT family member, WNT3.
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The OMP–lacZ Transgene Mimics the Unusual Expression Pattern of OR-Z6, a New Odorant Receptor Gene on Mouse Chromosome 6: Implication for Locus-Dependent Gene Expression
Martina Pyrski,Zheng Xu,Eric L. Walters,Debra J. Gilbert,Nancy A. Jenkins,Neal G. Copeland,Frank L. Margolis +6 more
TL;DR: Results suggest that the expression of both genes is coordinated and that transgene expression in H-lacZ6 mice is regulated by locus-dependent mechanisms.