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Nancy A. Jenkins
Researcher at Houston Methodist Hospital
Publications - 743
Citations - 105243
Nancy A. Jenkins is an academic researcher from Houston Methodist Hospital. The author has contributed to research in topics: Gene & Gene mapping. The author has an hindex of 155, co-authored 741 publications receiving 101587 citations. Previous affiliations of Nancy A. Jenkins include Institute of Molecular and Cell Biology & University of Texas MD Anderson Cancer Center.
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Genomic structure and mapping of precerebellin and a precerebellin-related gene.
TL;DR: The cloning of the murine homolog of precerebellin, C Bln1, and a closely related gene, Cbln2 is reported, which is 88% identical to the carboxy terminal region of CBln1.
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Fine Mapping of the Friend Retrovirus Resistance Gene, Rfv3, on Mouse Chromosome 15
Heidi J. Super,Kim J. Hasenkrug,Stacey Simmons,Diane M. Brooks,Roberta Konzek,Kevin D. Sarge,Richard I. Morimoto,Nancy A. Jenkins,Debra J. Gilbert,Neal G. Copeland,Wayne N. Frankel,Bruce Chesebro +11 more
TL;DR: In this article, the location of the Rfv3 gene was localized to a 0.83-cM region by using microsatellite markers and progeny tests to accurately determine the phenotype of recombinant mice.
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Two-Step Forward Genetic Screen in Mice Identifies Ral GTPase-Activating Proteins as Suppressors of Hepatocellular Carcinoma
Takahiro Kodama,Emilie A. Bard-Chapeau,Justin Y. Newberg,Michiko Kodama,Roberto Rangel,Kosuke Yoshihara,Jerrold M. Ward,Nancy A. Jenkins,Neal G. Copeland +8 more
TL;DR: Members of the Ral guanosine triphosphatase-activating protein pathway and other proteins as suppressors of HCC cell proliferation and tumor growth might serve as therapeutic targets for liver cancer.
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Proviral integrations at the Evi5 locus disrupt a novel 90 kDa protein with homology to the Tre2 oncogene and cell-cycle regulatory proteins.
TL;DR: While blast searches indicated that Evi 5 is a novel gene, homologies were detected between Evi5 and a known oncogene, Tre2, as well as mammalian and yeast cell cycle regulatory proteins.
Journal Article
Expression of human IFN-gamma genomic DNA in transgenic mice.
Howard A. Young,K. L. Komschlies,V. Ciccarone,Margaret Beckwith,Michael P. Rosenberg,Nancy A. Jenkins,Neal G. Copeland,Scott K. Durum +7 more
TL;DR: The introduced 8.6-kb fragment of human genomic DNA containing the full length IFN-gamma gene into the mouse germline indicates that the regulatory elements for this gene are completely preserved over the phylogenetic distance separating mouse and man, even though substantial drift has occurred in the structural gene.