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Nancy A. Jenkins
Researcher at Houston Methodist Hospital
Publications - 743
Citations - 105243
Nancy A. Jenkins is an academic researcher from Houston Methodist Hospital. The author has contributed to research in topics: Gene & Gene mapping. The author has an hindex of 155, co-authored 741 publications receiving 101587 citations. Previous affiliations of Nancy A. Jenkins include Institute of Molecular and Cell Biology & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
Voltage-Gated Potassium Channel Genes Are Clustered in Paralogous Regions of the Mouse Genome
Leslie F. Lock,Debra J. Gilbert,Valerie A. Street,Mary B. Migeon,Nancy A. Jenkins,Neal G. Copeland,Bruce L. Tempel +6 more
TL;DR: The genetic mapping of 12-16 different murine, voltage-gated K channel genes suggests that the K channel gene subfamilies arose through ancient localized gene duplication events, followed by chromosomal duplications and rearrangements as well as further gene duplication.
Journal ArticleDOI
Genetic organization of the agouti region of the mouse.
Linda D. Siracusa,Liane B. Russell,Eva M. Eicher,Dorcas J. Corrow,Neal G. Copeland,Nancy A. Jenkins +5 more
TL;DR: A conceptual framework for initiating chromosome walking experiments designed to retrieve sequences from the agouti locus is provided and new insight is given into the genetic organization of the ag outi region.
Journal Article
His-1 and His-2: identification and chromosomal mapping of two commonly rearranged sites of viral integration in a myeloid leukemia.
David S. Askew,Christopher Bartholomew,Arthur M. Buchberg,Marc Valentine,Nancy A. Jenkins,Neal G. Copeland,James N. Ihle +6 more
TL;DR: The His-1 locus maps to mouse chromosome 2 distinct from any known oncogene or common site of integration but near the proximal breakpoint for a deletion that is observed in over 90% of radiation-induced leukemias.
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Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification.
Liming Chen,Piroon Jenjaroenpun,Andrea Mun Ching Pillai,Anna V. Ivshina,Ghim Siong Ow,Motakis Efthimios,Tang Zhiqun,Tuan Zea Tan,Song-Choon Lee,Keith Rogers,Jerrold M. Ward,Seiichi Mori,David J. Adams,Nancy A. Jenkins,Neal G. Copeland,Kenneth Hon Kim Ban,Vladimir A. Kuznetsov,Jean Paul Thiery +17 more
TL;DR: In vivo transposon-based forward genetic screening in mice is used to identify potentially relevant BC driver genes and six gene pairs that could prognose human BC subtypes into high-, intermediate-, and low-risk groups with high confidence and reproducibility are identified.
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The mouse CREB (cAMP responsive element binding protein) gene: structure, promoter analysis, and chromosomal localization.
Tim J Cole,Neal G. Copeland,Debra J. Gilbert,Nancy A. Jenkins,Günther Schütz,Siegfried Ruppert +5 more
TL;DR: The CREB gene was found to be single copy in the mouse and well conserved through evolution and Creb-1, the CREB locus, was mapped to the proximal region of mouse chromosome 1.