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Nancy A. Jenkins
Researcher at Houston Methodist Hospital
Publications - 743
Citations - 105243
Nancy A. Jenkins is an academic researcher from Houston Methodist Hospital. The author has contributed to research in topics: Gene & Gene mapping. The author has an hindex of 155, co-authored 741 publications receiving 101587 citations. Previous affiliations of Nancy A. Jenkins include Institute of Molecular and Cell Biology & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
Angiopoietins 3 and 4: Diverging gene counterparts in mice and humans
David M. Valenzuela,Jennifer A. Griffiths,Rojas Jose F,Aldrich Thomas H,Pamela F. Jones,Hao Zhou,Joyce McClain,Neal G. Copeland,Debra J. Gilbert,Nancy A. Jenkins,Tammy T. Huang,Nick Papadopoulos,Maisonpierre Peter C,Samuel Davis,George D. Yancopoulos +14 more
TL;DR: The angiopoietins have recently joined the members of the vascular endothelial growth factor family as the only known growth factors largely specific for vascular endothelium as discussed by the authors, and they include a naturally occurring agonist, angioietin-1, as well as an naturally occurring antagonist, angiopooietin2, both of which act by means of the Tie2 receptor.
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The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells
Karen B. Avraham,Tama Hasson,Karen P. Steel,David M. Kingsley,Liane B. Russell,Mark S. Mooseker,Neal G. Copeland,Nancy A. Jenkins +7 more
TL;DR: It is shown that Snell's waltzer encodes an unconventional myosin heavy chain,Myosin VI, which is expressed within the sensory hair cells of the inner ear, and appears to be required for maintaining their structural integrity.
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Molecular basis of mouse microphthalmia ( mi ) mutations helps explain their developmental and phenotypic consequences
Eiríkur Steingrímsson,Karen J. Moore,M. Lynn Lamoreux,Adrian R. Ferré-D'Amaré,Stephen K. Burley,Debra C. Sanders Zimring,Loren C. Skow,Colin A. Hodgkinson,Heinz Arnheiter,Neal G. Copeland,Nancy A. Jenkins +10 more
TL;DR: The molecular defects associated with eight murine mi mutations are characterized, which vary in both their mode of inheritance and in the cell types they affect.
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The Promise of Comparative Genomics in Mammals
Stephen J. O'Brien,Marilyn Menotti-Raymond,William J. Murphy,William G. Nash,Johannes Wienberg,Roscoe Stanyon,Neal G. Copeland,Nancy A. Jenkins,James E. Womack,Jennifer A. Marshall Graves +9 more
TL;DR: Comparative genetic assessment expands the utility of dense genetic maps of human, mouse, and rat genomes in gene discovery, in functional genomics, and in tracking the evolutionary forces that sculpted the genome organization of modern mammalian species.
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TLR6: A novel member of an expanding Toll-like receptor family
Osamu Takeuchi,Takao Kawai,Hideki Sanjo,Neal G. Copeland,Debra J. Gilbert,Nancy A. Jenkins,Kiyoshi Takeda,Shizuo Akira +7 more
TL;DR: The molecular cloning and characterization of a new member of Toll-like receptor family, Toll- like receptor 6 (TLR6) is reported, suggesting that TLR6 is a novel member of an expanding TLR family.