N
Nathalie Griffon
Researcher at French Institute of Health and Medical Research
Publications - 56
Citations - 3897
Nathalie Griffon is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Dopamine receptor D3 & Dopamine receptor D2. The author has an hindex of 29, co-authored 56 publications receiving 3784 citations.
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Journal ArticleDOI
BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization.
Olivier Guillin,Jorge Diaz,Patrick Carroll,Nathalie Griffon,Jean-Charles Schwartz,Pierre Sokoloff +5 more
TL;DR: It is shown that BDNF from dopamine neurons is responsible for inducing normal expression of the dopamine D3 receptor in nucleus accumbens both during development and in adulthood, and may be an important determinant of pathophysiological conditions such as drug addiction, schizophrenia or Parkinson's disease.
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Phenotypical characterization of neurons expressing the dopamine D3 receptor in the rat brain
Jorge Diaz,D. Levesque,C.H. Lammers,Nathalie Griffon,Marie-Pascale Martres,J.-C. Schwartz,Pierre Sokoloff +6 more
TL;DR: The occurrence of D3 receptor gene expression in some brain areas receiving low dopamine innervation supports the hypothesis that this receptor may mediate non-synaptic actions of dopamine.
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A functional test identifies dopamine agonists selective for D3 versus D2 receptors.
TL;DR: The known behavioural actions of D3 selective agonists support a role for the D3 receptor in motor inhibitions, which should be taken into account for the treatment of motor dysfunctions by dopamine agonists.
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D2/D3 dopamine receptor heterodimers exhibit unique functional properties.
Marco Scarselli,Francesca Novi,Ester Schallmach,Ridwan Lin,Alessandra Baragli,Anna Colzi,Nathalie Griffon,Giovanni Umberto Corsini,Pierre Sokoloff,Robert Levenson,Zvi Vogel,Roberto Maggio +11 more
TL;DR: Coimmunoprecipitation experiments indicate that D2 and D3 receptors are capable of physical interaction and form complexes with these fragments and that these complexes bind [3H]nemonapride less efficiently or are not correctly targeted to the membrane.
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Molecular cloning and characterization of the rat fifth melanocortin receptor.
Nathalie Griffon,Virginie Mignon,Patricia Facchinetti,Jean-Jacques Diaz,J.-C. Schwartz,Pierre Sokoloff +5 more
TL;DR: The cloning, pharmacological characterization and expression of the rat fifth melanocortin receptor (MC5) is reported, starting from the dopamine D3 receptor sequence to screen a genomic DNA library.