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Netta Mendelson Cohen
Researcher at Weizmann Institute of Science
Publications - 14
Citations - 2944
Netta Mendelson Cohen is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Epigenomics & DNA methylation. The author has an hindex of 9, co-authored 11 publications receiving 2110 citations. Previous affiliations of Netta Mendelson Cohen include Israel Institute for Biological Research.
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Journal ArticleDOI
Multiscale 3D Genome Rewiring during Mouse Neural Development
Boyan B. Bonev,Netta Mendelson Cohen,Quentin Szabo,Lauriane Fritsch,Giorgio L. Papadopoulos,Yaniv Lubling,Xiaole Xu,Xiaodan Lv,Jean-Philippe Hugnot,Amos Tanay,Giacomo Cavalli +10 more
TL;DR: This work comprehensively mapped 3D chromatin organization during mouse neural differentiation in vitro and in vivo, generating the highest-resolution Hi-C maps available to date and shows that multiple factors influence the dynamics of chromatin interactions in development.
Journal ArticleDOI
Cell-cycle dynamics of chromosomal organization at single-cell resolution
Takashi Nagano,Yaniv Lubling,Csilla Várnai,Carmel Dudley,Wing Leung,Yael Baran,Netta Mendelson Cohen,Steven W. Wingett,Peter Fraser,Peter Fraser,Amos Tanay +10 more
TL;DR: It is shown that chromosomal compartments, topological-associated domains (TADs), contact insulation and long-range loops, all defined by bulk Hi-C maps, are governed by distinct cell-cycle dynamics, while loops are generally stable from G1 to S and G2 phase.
Journal ArticleDOI
Prediction of acute myeloid leukaemia risk in healthy individuals
Sagi Abelson,Grace Collord,Grace Collord,Stanley W.K. Ng,Omer Weissbrod,Netta Mendelson Cohen,Elisabeth Niemeyer,Noam Barda,Philip C. Zuzarte,Lawrence E. Heisler,Yogi Sundaravadanam,Robert Luben,Shabina Hayat,Ting Ting Wang,Ting Ting Wang,Zhen Zhao,Iulia Cirlan,Trevor J. Pugh,Trevor J. Pugh,Trevor J. Pugh,David Soave,Karen Ng,Calli Latimer,Claire Hardy,Keiran Raine,David T. Jones,Diana Hoult,Abigail Britten,John Douglas Mcpherson,Mattias Johansson,Faridah Mbabaali,Jenna Eagles,Jessica Miller,Danielle Pasternack,Lee Timms,Paul M. Krzyzanowski,Philip Awadalla,Rui Costa,Eran Segal,Scott V. Bratman,Scott V. Bratman,Scott V. Bratman,Philip A. Beer,Sam Behjati,Sam Behjati,Inigo Martincorena,Jean C.Y. Wang,Jean C.Y. Wang,Jean C.Y. Wang,Kristian M. Bowles,Kristian M. Bowles,J. Ramón Quirós,Anna Karakatsani,Carlo La Vecchia,Antonia Trichopoulou,Elena Salamanca-Fernández,José María Huerta,Aurelio Barricarte,Ruth C. Travis,Rosario Tumino,Giovanna Masala,Heiner Boeing,Salvatore Panico,Rudolf Kaaks,Alwin Krämer,Sabina Sieri,Elio Riboli,Paolo Vineis,Matthieu Foll,James McKay,Silvia Polidoro,Núria Sala,Kay-Tee Khaw,Roel Vermeulen,Peter J. Campbell,Peter J. Campbell,Elli Papaemmanuil,Elli Papaemmanuil,Mark D. Minden,Amos Tanay,Ran D. Balicer,Nicholas J. Wareham,Moritz Gerstung,Moritz Gerstung,John E. Dick,John E. Dick,Paul Brennan,George S. Vassiliou,George S. Vassiliou,Liran I. Shlush,Liran I. Shlush +90 more
TL;DR: Deep sequencing is used to analyse genes that are recurrently mutated in AML to distinguish between individuals who have a high risk of developing AML and those with benign ARCH, providing proof-of-concept that it is possible to discriminate ARCH from pre-AML many years before malignant transformation.
Journal ArticleDOI
Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues
Gilad Landan,Netta Mendelson Cohen,Zohar Mukamel,Amir Bar,Alina Molchadsky,Ran Brosh,Shirley Horn-Saban,Daniela Amann Zalcenstein,Naomi Goldfinger,Adi Zundelevich,Einav Nili Gal-Yam,Varda Rotter,Amos Tanay +12 more
TL;DR: It is shown that methylation patterns within populations of cells from individual somatic tissues are heterogeneous and polymorphic, and that changes in the susceptibility to methylation accumulation are correlated with changes in histone modification and CTCF occupancy.
Posted ContentDOI
Cell cycle dynamics of chromosomal organisation at single-cell resolution
Takashi Nagano,Yaniv Lubling,Csilla Várnai,Carmel Dudley,Wing Leung,Yael Baran,Netta Mendelson Cohen,Steven W. Wingett,Peter Fraser,Amos Tanay +9 more
TL;DR: It is shown that chromosomal compartments, topological domains, contact insulation and long-range loops, all defined by ensemble Hi-C maps, are governed by distinct cell cycle dynamics, while DNA replication correlates with build-up of compartments and reduction in TAD insulation, while loops are generally stable from G1 through S and G2.