Núria Sala

TL;DR: Deep sequencing is used to analyse genes that are recurrently mutated in AML to distinguish between individuals who have a high risk of developing AML and those with benign ARCH, providing proof-of-concept that it is possible to discriminate ARCH from pre-AML many years before malignant transformation.

TL;DR: The scientific data on the role of genetic factors in gastric cancer risk are promising, but the lack of association reported so far should be considered with caution due to significant limitations in study design.

TL;DR: Patients with familial, recurrent, spontaneous or juvenile venous thrombosis, combined with combined clinical factors, had a higher risk of carrying some deficiency and laboratory evaluation ofThrombotic patients is advisable, especially if some of these clinical factors are present.

TL;DR: While insulin resistance is often considered secondary to obesity, the association of the insulin resistance score with lower BMI and adiposity and with incident T2D even among individuals of normal weight highlights the role of insulin resistance and ectopic fat distribution in type 2 diabetes, independently of body size.

TL;DR: A first record of identified mutations was undertaken in 1996 under the auspices of the International Society on Thrombosis and Haemostasis Scientific and Standardization Committee (ISTH SSC) and was published in 1997, and this first database reported mutations identified in 126 protein S-deficient subjects.