Nicole L. Rosin

TL;DR: In vivo results showed that LNP siRNA systems containing DLinKC2-DMA are effective agents for silencing GAPDH in APCs in the spleen and peritoneal cavity following systemic administration.

TL;DR: It is demonstrated that after injury, including in humans, macrophages function to clear debris and persist within the nerve microenvironment and highlight a molecular mechanism by which this occurs.

TL;DR: An extensive review of studies that have used second harmonic generation imaging in skin, lung, cardiovascular, tendon and ligaments, and eye tissue to understand alterations in fibrillar collagens in scar tissue and the current methods of image analysis are reviewed.

TL;DR: It is shown that hair follicle mesenchymal progenitors make limited contributions to wound repair, and pharmacological modulation of RUNX1 and retinoic acid signaling or genetic deletion of Hic1 within wound-activated fibroblasts was sufficient to modulate healing outcomes, suggesting that reparative fibro Blasts have latent but modifiable regenerative capacity.

TL;DR: A Chlamydia vaccine based on the recombinant proteins PmpG-1, PmpE/F-2, and MOMP delivered in a DDA/TDB adjuvant conferred protection against infection that correlated with IFN-γ/TNF-α and IFN -γ/IL-17 double-positive CD4+ T cells.