N
Niels-Peter Becker
Researcher at Charité
Publications - 21
Citations - 607
Niels-Peter Becker is an academic researcher from Charité. The author has contributed to research in topics: Selenoprotein & Selenoprotein P. The author has an hindex of 11, co-authored 20 publications receiving 456 citations. Previous affiliations of Niels-Peter Becker include Humboldt University of Berlin.
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Journal ArticleDOI
Selenium status is associated with colorectal cancer risk in the European prospective investigation of cancer and nutrition cohort
David J. Hughes,Veronika Fedirko,Mazda Jenab,Lutz Schomburg,Catherine Méplan,Heinz Freisling,Hendrik B. Bueno-de-Mesquita,Sandra Hybsier,Niels-Peter Becker,Magdalena Czuban,Anne Tjønneland,Malene Outzen,Marie-Christine Boutron-Ruault,Marie-Christine Boutron-Ruault,Antoine Racine,Antoine Racine,Nadia Bastide,Nadia Bastide,Tilman Kühn,Rudolf Kaaks,Dimitrios Trichopoulos,Antonia Trichopoulou,Pagona Lagiou,Pagona Lagiou,Salvatore Panico,Petra H.M. Peeters,Elisabete Weiderpass,Guri Skeie,Engeset Dagrun,María Dolores Chirlaque,María José Sánchez,Eva Ardanaz,Ingrid Ljuslinder,Maria Wennberg,Kathryn E. Bradbury,Paolo Vineis,Alessio Naccarati,Domenico Palli,Heiner Boeing,Kim Overvad,Miren Dorronsoro,Paula Jakszyn,Amanda J. Cross,José Ramón Quirós,Magdalena Stepien,So Yeon Kong,Talita Duarte-Salles,Elio Riboli,John E. Hesketh +48 more
TL;DR: The findings indicate that Se status is suboptimal in many Europeans and suggest an inverse association between CRC risk and higher serum Se status, which is more evident in women.
Journal ArticleDOI
Pre-diagnostic copper and zinc biomarkers and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort
Magdalena Stepien,Mazda Jenab,Heinz Freisling,Niels-Peter Becker,Magdalena Czuban,Anne Tjønneland,Anja Olsen,Kim Overvad,Marie-Christine Boutron-Ruault,Marie-Christine Boutron-Ruault,Francesca Mancini,Francesca Mancini,Isabelle Savoye,Isabelle Savoye,Verena Katzke,Tilman Kühn,Heiner Boeing,Khalid Iqbal,Antonia Trichopoulou,Christina Bamia,Philippos Orfanos,Domenico Palli,Sabina Sieri,Rosario Tumino,Alessio Naccarati,Salvatore Panico,Hendrik B. Bueno-de-Mesquita,Petra H.M. Peeters,Petra H.M. Peeters,Elisabete Weiderpass,Susana Merino,Paula Jakszyn,María José Sánchez,Miren Dorronsoro,José María Huerta,Aurelio Barricarte,Stina Bodén,Behany van Guelpen,Nicholas J. Wareham,Kay-Tee Khaw,Kathryn E. Bradbury,Amanda J. Cross,Lutz Schomburg,David J. Hughes +43 more
TL;DR: Copper or copper levels in relation to zinc (copper to zinc ratio) become imbalanced in the process of CRC development, suggesting a possible role for higher copper and copper/zinc ratio levels in CRC development and progression.
Journal ArticleDOI
Cooking of meat and fish in Europe: Results from the European Prospective Investigation into Cancer and Nutrition (EPIC)
S. Rohrmann,J. Linseisen,Niels-Peter Becker,Teresa Norat,Rashmi Sinha,Guri Skeie,Eiliv Lund,Carmen Enid Martínez,Aurelio Barricarte,Iréne Mattisson,G Berglund,Ailsa A Welch,Gwyneth K. Davey,Kim Overvad,Anne Tjønneland,Françoise Clavel-Chapelon,Emmanuelle Kesse,G Lotze,Kerstin Klipstein-Grobusch,Effie Vasilopoulou,Evangelos Polychronopoulos,Valeria Pala,Egidio Celentano,H. B. Bueno-De-Mesquita,P. H. M. Peeters,Elio Riboli,Nadia Slimani +26 more
TL;DR: High variation in both the kind of meat/fish consumed as well as its cooking methods is observed within the EPIC cohort, and in order to use this variation for the evaluation of the impact of cooking methods on cancer risk, a questionnaire is being developed and could be applied in the whole EPic cohort.
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An Improved Nonradioactive Screening Method Identifies Genistein and Xanthohumol as Potent Inhibitors of Iodothyronine Deiodinases
Kostja Renko,Sonja Schäche,Carolin S. Hoefig,Tim Welsink,Christian Schwiebert,Doreen Braun,Niels-Peter Becker,Josef Köhrle,Lutz Schomburg +8 more
TL;DR: A rapid nonradioactive screening method based on the Sandell-Kolthoff reaction is suitable for identification of environmental, nutritive and pharmacological compounds modulating activities of human deiodinase enzymes.
Journal ArticleDOI
Hypoxia reduces and redirects selenoprotein biosynthesis.
Niels-Peter Becker,Janine Martitz,Kostja Renko,Mette Stoedter,Sandra Hybsier,Thorsten Cramer,Lutz Schomburg +6 more
TL;DR: Substitute selenium is able to overcome the hypoxia-dependent down regulation of selenoprotein expression in the cell culture model system, supporting the concept of using se lenium as an adjuvant treatment option in severe diseases.