O
Onno W. Akkerman
Researcher at University Medical Center Groningen
Publications - 150
Citations - 2916
Onno W. Akkerman is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Tuberculosis & Medicine. The author has an hindex of 23, co-authored 118 publications receiving 1898 citations. Previous affiliations of Onno W. Akkerman include University of Groningen.
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Journal ArticleDOI
Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis
Nafees Ahmad,Shama D. Ahuja,Onno W. Akkerman,Jan-Willem C. Alffenaar,Laura F Anderson,Parvaneh Baghaei,Didi Bang,Pennan M. Barry,Mayara Lisboa Bastos,Digamber Behera,Andrea Benedetti,Gregory P. Bisson,Martin J. Boeree,Maryline Bonnet,Sarah K. Brode,James C.M. Brust,Ying Cai,Eric Caumes,J. Peter Cegielski,Rosella Centis,Pei-Chun Chan,Edward D. Chan,Kwok-Chiu Chang,Macarthur Charles,Andra Cirule,Margareth Pretti Dalcolmo,Lia D'Ambrosio,Gerard de Vries,Keertan Dheda,Aliasgar Esmail,Jennifer Flood,Gregory J. Fox,Mathilde Fréchet-Jachym,Geisa Fregona,Regina Gayoso,Medea Gegia,Maria Tarcela Gler,Sue Gu,Lorenzo Guglielmetti,Timothy H. Holtz,Jennifer Hughes,Petros Isaakidis,Leah G. Jarlsberg,Russell R. Kempker,Salmaan Keshavjee,Faiz Ahmad Khan,Maia Kipiani,Serena P. Koenig,Won-Jung Koh,Afranio Lineu Kritski,Liga Kuksa,Charlotte Kvasnovsky,Nakwon Kwak,Zhiyi Lan,Christoph Lange,Rafael Laniado-Laborín,Myungsun Lee,Vaira Leimane,Chi-Chiu Leung,Eric Chung Ching Leung,Pei Zhi Li,Phil Lowenthal,Ethel Leonor Noia Maciel,Suzanne M. Marks,Sundari Mase,Lawrence Mbuagbaw,Giovanni Battista Migliori,Vladimir Milanov,Ann C. Miller,Carole D. Mitnick,Chawangwa Modongo,Erika Mohr,Ignacio Monedero,Payam Nahid,Norbert Ndjeka,Max R. O'Donnell,Nesri Padayatchi,Domingo Palmero,Jean W. Pape,Laura Jean Podewils,Ian R Reynolds,Vija Riekstina,Jérôme Robert,Maria I. Rodriguez,Barbara Seaworth,Kwonjune J. Seung,Kathryn Schnippel,Tae Sun Shim,Rupak Singla,Sarah Smith,Giovanni Sotgiu,Ganzaya Sukhbaatar,Payam Tabarsi,Simon Tiberi,Anete Trajman,Lisa Trieu,Zarir F Udwadia,Tjip S. van der Werf,Nicolas Veziris,Piret Viiklepp,Stalz Charles Vilbrun,Kathleen F. Walsh,Janice Westenhouse,Wing Wai Yew,Jae-Joon Yim,Nicola M. Zetola,Matteo Zignol,Dick Menzies +107 more
TL;DR: Treatment outcomes were significantly better with use of linezolid, later generation fluoroquinolones, bedaquiline, clofazimine, and carbapenems for treatment of multidrug-resistant tuberculosis, and the need for trials to ascertain the optimal combination and duration of these drugs is emphasised.
Journal ArticleDOI
Effectiveness and safety of bedaquiline-containing regimens in the treatment of MDR- and XDR-TB: a multicentre study
Sergey Borisov,Keertan Dheda,Martin Enwerem,Rodolfo Romero Leyet,Lia D'Ambrosio,Rosella Centis,Giovanni Sotgiu,Simon Tiberi,Simon Tiberi,Jan-Willem C. Alffenaar,Andrey Maryandyshev,Evgeny Belilovski,Shashank Ganatra,Alena Skrahina,Onno W. Akkerman,Alena Aleksa,Rohit Amale,Janina Artsukevich,Judith Bruchfeld,Jose A. Caminero,Isabel Carpena Martinez,Luigi Codecasa,Margareth Pretti Dalcolmo,Justin T Denholm,Paul Douglas,Raquel Duarte,Aliasgar Esmail,Mohammed Fadul,Alexey Filippov,Lina Davies Forsman,Mina Gaga,Julia Amaranta Garcia-Fuertes,José-María García-García,Gina Gualano,Jerker Jonsson,Heinke Kunst,Jillian S.Y. Lau,Barbara Lazaro Mastrapa,Jorge Lazaro Teran Troya,Selene Manga,Katerina Manika,Pablo González Montaner,Jai B Mullerpattan,Suzette Oelofse,Martina Ortelli,Domingo Palmero,Fabrizio Palmieri,Antonella Papalia,Apostolos Papavasileiou,Marie-Christine Payen,Emanuele Pontali,Carlos Robalo Cordeiro,Laura Saderi,Tsetan Dorji Sadutshang,Tatsiana Sanukevich,Varvara Solodovnikova,Antonio Spanevello,Sonam Topgyal,Federica Toscanini,Adrian R Tramontana,Zarir F Udwadia,Pietro Viggiani,Veronica White,Alimuddin Zumla,Giovanni Battista Migliori +64 more
TL;DR: Bedaquiline-containing regimens achieved high conversion and success rates under different nonexperimental conditions, and is safe and effective in treating MDR- and XDR-TB patients.
Journal ArticleDOI
Worldwide Effects of Coronavirus Disease Pandemic on Tuberculosis Services, January-April 2020.
Giovanni Battista Migliori,Pei Min Thong,Onno W. Akkerman,Jan-Willem C. Alffenaar,Fernando Álvarez-Navascués,Mourtala Mohamed Assao-Neino,Pascale Valérie Bernard,Joshua Sorba Biala,François-Xavier Blanc,Elena M. Bogorodskaya,Sergey Borisov,Danilo Buonsenso,Marianne Calnan,Paola Castellotti,Rosella Centis,Jeremiah Chakaya,Jeremiah Chakaya,Jeremiah Chakaya,Jin-Gun Cho,Luigi Codecasa,Lia D'Ambrosio,Justin T Denholm,Martin Enwerem,Maurizio Ferrarese,Tatiana Senna Galvão,Marta García-Clemente,José-María García-García,Gina Gualano,José Antonio Gullón-Blanco,Sandra Inwentarz,Giuseppe Ippolito,Heinke Kunst,Andrei Maryandyshev,Mario Melazzini,Fernanda Carvalho de Queiroz Mello,Marcela Muñoz-Torrico,Patrick Bung Njungfiyini,Domingo Palmero,Fabrizio Palmieri,Pavilio Piccioni,Alberto Piubello,Adrian Rendon,Josefina Sabriá,Matteo Saporiti,Paola Scognamiglio,Samridhi Sharma,Denise Rossato Silva,Mahamadou Bassirou Souleymane,Antonio Spanevello,Eva Tabernero,Marina Tadolini,Michel Eke Tchangou,Alice Boi Yatta Thornton,Simon Tiberi,Zarir F Udwadia,Giovanni Sotgiu,Catherine W.M. Ong,Delia Goletti +57 more
TL;DR: Data showed that attendance at tuberculosis centers was lower during the first 4 months of the pandemic in 2020 than for the same period in 2019.
Journal ArticleDOI
MDR/XDR-TB management of patients and contacts: challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network.
Giovanni Battista Migliori,Simon Tiberi,Simon Tiberi,Alimuddin Zumla,Eskild Petersen,Jeremiah Chakaya,Jeremiah Chakaya,Christian Wejse,Marcela Muñoz Torrico,Raquel Duarte,Jan-Willem C. Alffenaar,Jan-Willem C. Alffenaar,Jan-Willem C. Alffenaar,H. Simon Schaaf,Ben J. Marais,Daniela Maria Cirillo,Riccardo Alagna,Adrian Rendon,Emanuele Pontali,Alberto Piubello,Jose Figueroa,Gabriella Ferlazzo,Alberto L. García-Basteiro,Alberto L. García-Basteiro,Rosella Centis,Dina Visca,Lia D'Ambrosio,Giovanni Sotgiu,T. Abu Arkub,Onno W. Akkerman,Alena Aleksa,Evgeny Belilovski,Enrique Bernal,F-X. Blanc,Martin J. Boeree,Sergey Borisov,Judith Bruchfeld,J. Cadiñanos Loidi,Jose A. Caminero,Anna Cristina Calçada Carvalho,J.J. Cebrian Gallardo,Charalampos,Edvardas Danila,L. Davies Forsman,Justin T Denholm,Keertan Dheda,Roland Diel,Saulius Diktanas,Claudia C. Dobler,Martin Enwerem,Susanna Esposito,N. Escobar Salinas,Alex Filippov,B. Formenti,J.M. García García,Delia Goletti,R. Gomez Rosso,Gina Gualano,Petros Isaakidis,Anna Kaluzhenina,S. Koirala,Liga Kuksa,Heinke Kunst,Yang Li,Cecile Magis-Escurra,Vinicio Manfrin,Selene Manga,Katerina Manika,Valentina Marchese,E. Martínez Robles,Andrey Maryandyshev,Alberto Matteelli,Alessandro Wasum Mariani,Jesica Mazza-Stalder,Fernanda Carvalho de Queiroz Mello,L. Mendoza,A. Mesi,Skaidrius Miliauskas,H. Mustafa Hamdan,Norbert Ndjeka,M. Nieto Marcos,Tom H. M. Ottenhoff,Domingo Palmero,Fabrizio Palmieri,Apostolos Papavasileiou,Marie-Christine Payen,Agostina Pontarelli,M. Pretti Dalcolmo,S. Quirós Fernandez,R. Romero,D. Rossato Silva,A.P. Santos,Barbara Seaworth,M. Sinitsyn,Alena Skrahina,Ivan Solovic,Antonio Spanevello,Marina Tadolini,C. Torres,Zarir F Udwadia,M. van den Boom,Grigory V. Volchenkov,Askar Yedilbayev,R. Zaleskis,Jean-Pierre Zellweger +104 more
TL;DR: The review comprehensively describes the latest information on contact tracing and LTBI management in MDR-TB contacts, while providing guidance on post-treatment functional evaluation and rehabilitation of TB sequelae, infection control and other public health priorities.
Journal ArticleDOI
Surveillance of adverse events in the treatment of drug-resistant tuberculosis: first global report
Sergey Borisov,Edvardas Danila,Andrei Maryandyshev,Margareth Pretti Dalcolmo,Skaidrius Miliauskas,Liga Kuksa,Selene Manga,Alena Skrahina,Saulius Diktanas,Luigi Codecasa,Alena Aleksa,Judith Bruchfeld,Judith Bruchfeld,Antoniya Koleva,Alberto Piubello,Zarir F Udwadia,Onno W. Akkerman,Evgeny Belilovski,Enrique Bernal,Martin J. Boeree,Julen Cadiñanos Loidi,Qingshan Cai,Jose Joaquin Cebrian Gallardo,Masoud Dara,Edita Davidavičienė,Lina Davies Forsman,Lina Davies Forsman,Jorge De Los Rios,Justin T Denholm,Jacinta Drakšienė,Raquel Duarte,Seifeldin Eltaeb Elamin,Nadia Escobar Salinas,Maurizio Ferrarese,Alexey Filippov,Ana Garcia,José-María García-García,Ieva Gaudiesiute,Blagovesta Gavazova,Regina Gayoso,R. Rosso,Vygantas Gruslys,Gina Gualano,Wouter Hoefsloot,Jerker Jonsson,Elena Khimova,Heinke Kunst,Rafael Laniado-Laborín,Yang Li,Cecile Magis-Escurra,Vinicio Manfrin,Valentina Marchese,Elena Martínez Robles,Alberto Matteelli,Jesica Mazza-Stalder,Charalampos Moschos,Marcela Muñoz-Torrico,Hamdan Mustafa Hamdan,Birutė Nakčerienė,Laurent P. Nicod,Magnolia Nieto Marcos,Domingo Palmero,Fabrizio Palmieri,Apostolos Papavasileiou,Marie-Christine Payen,Agostina Pontarelli,Sarai Quirós,Adrian Rendon,Laura Saderi,Agnese Šmite,Ivan Solovic,Mahamadou Bassirou Souleymane,Marina Tadolini,Martin van den Boom,Marisa Vescovo,Pietro Viggiani,Askar Yedilbayev,Rolandas Zablockis,Dmitry Zhurkin,Matteo Zignol,Dina Visca,Antonio Spanevello,Jose A. Caminero,Jan-Willem C. Alffenaar,Simon Tiberi,Simon Tiberi,Rosella Centis,Lia D'Ambrosio,Emanuele Pontali,Giovanni Sotgiu,Giovanni Battista Migliori +90 more
TL;DR: This global project (658 patients from 26 countries) demonstrates aDSM is feasible and serious adverse events of recommended drugs are reasonably low (overall 57 out of 504, 11.3%), but implementation needs scaling up to support patient-centred care.