O
Oscar Hernández-Hernández
Researcher at Necker-Enfants Malades Hospital
Publications - 39
Citations - 490
Oscar Hernández-Hernández is an academic researcher from Necker-Enfants Malades Hospital. The author has contributed to research in topics: Spinocerebellar ataxia & Myotonic dystrophy. The author has an hindex of 13, co-authored 33 publications receiving 388 citations. Previous affiliations of Oscar Hernández-Hernández include CINVESTAV & Instituto Politécnico Nacional.
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Journal ArticleDOI
Myotonic dystrophy CTG expansion affects synaptic vesicle proteins, neurotransmission and mouse behaviour
Oscar Hernández-Hernández,Céline Guiraud-Dogan,Géraldine Sicot,Aline Huguet,Sabrina Luilier,Esther Steidl,Stefanie Saenger,Elodie Marciniak,Hélène Obriot,Caroline Chevarin,Annie Nicole,Lucile Revillod,Konstantinos Charizanis,Kuang-Yung Lee,Kuang-Yung Lee,Yasuhiro Suzuki,Takashi Kimura,Tohru Matsuura,Bulmaro Cisneros,Maurice S. Swanson,F. Trovero,Bruno Buisson,Jean-Charles Bizot,Michel Hamon,Sandrine Humez,Guillaume Bassez,Friedrich Metzger,Luc Buée,Arnold Munnich,Nicolas Sergeant,Geneviève Gourdon,Mário Gomes-Pereira +31 more
TL;DR: A novel connection between physiological phenotypes and synaptic protein dysregulation, indicative of synaptic dysfunction in myotonic dystrophy type 1 brain pathology is found.
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Histamine-induced Ca2+ entry in human astrocytoma U373 MG cells: evidence for involvement of store-operated channels.
Margarita Barajas,Arturo Andrade,Oscar Hernández-Hernández,Ricardo Felix,José-Antonio Arias-Montaño +4 more
TL;DR: The results confirm the involvement of PKC in the regulation of H1 receptor‐induced responses and point out to the existence of a feedback mechanism acting via PKC to limit the increase in [Ca2+]i.
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Identification of a disulfide bridge essential for structure and function of the voltage-gated Ca2+ channel α2δ-1 auxiliary subunit
Aida Calderón-Rivera,Arturo Andrade,Oscar Hernández-Hernández,Ricardo González-Ramírez,Alejandro Sandoval,Manuel Rivera,Juan Carlos Gomora,Ricardo Felix +7 more
TL;DR: Two Cys residues are identified involved in the formation of an intermolecular disulfide bond of critical importance for the structure and function of the α(2)δ-1 subunit ofoltage-gated calcium channels.
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Recombinant human ZP3-induced sperm acrosome reaction: evidence for the involvement of T- and L-type voltage-gated calcium channels.
Omar José,Oscar Hernández-Hernández,Mayel Chirinos,María Elena González-González,Fernando Larrea,Angélica Almanza,Angélica Almanza,Ricardo Felix,Alberto Darszon,Claudia L. Treviño +9 more
TL;DR: Rec recombinant human ZP3 produced in baculovirus-infected Sf9 cells is used to investigate the involvement of Ca(V) channels in the human sperm AR, and overall findings suggest that Ca(v)1 and Ca( V)3 channels participate in human spermAR.
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Analysis of CAG repeats in five SCA loci in Mexican population: epidemiological evidence of a SCA7 founder effect
Jonathan J. Magaña,Y. S. Tapia-Guerrero,Luis Velázquez-Pérez,César M Cerecedo-Zapata,M. Maldonado-Rodríguez,Joan Jano-Ito,Norberto Leyva-García,Rigoberto González-Piña,Emilio Martínez-Cruz,Oscar Hernández-Hernández,Bulmaro Cisneros +10 more
TL;DR: Genotyping of 300 healthy individuals from Mexican population and compiled data from different ethnicities showed discordant results concerning the hypothesis that SCA disease alleles arise by expansion of large normal alleles.