P
Pascal De Tullio
Researcher at University of Liège
Publications - 128
Citations - 2442
Pascal De Tullio is an academic researcher from University of Liège. The author has contributed to research in topics: Benzothiadiazine & AMPA receptor. The author has an hindex of 26, co-authored 122 publications receiving 2106 citations. Previous affiliations of Pascal De Tullio include Université libre de Bruxelles.
Papers
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Journal ArticleDOI
Modulation of mitochondrial respiration rate and calcium-induced swelling by new cromakalim analogues.
Ange Mouithys-Mickalad,Justine Ceusters,Mounia Charif,Benaissa El Moualij,Mathieu Schoumacher,Simon Plyte,Thierry Franck,Lucien Bettendorff,Bernard Pirotte,Didier Serteyn,Pascal De Tullio +10 more
TL;DR: Results indicate that cromakalim, as parent molecule, does not induce per se any direct effect on mitochondrial respiratory function neither on whole cells nor on isolated mitochondria whereas both benzopyran analogues 1 and 2 display totally opposite behavior profiles, suggesting that compound 1, by increasing the maximal respiration capacity, might behave as a mild uncoupling agent and compound 2 is taken as an inhibitor of the mitochondrial electron-transfer chain.
Patent
Dihydrobenzopyran, thiochroman, tetrahydroquinoleine and tetrahydronaphtalene derivatives and their use in anticancer therapy
Pascal De Tullio,Xavier Florence,Eric Goffin,Robert Kiss,Delphine Lamoral-Theys,Florence Lefranc,Bernard Pirotte,Bernard Rogister +7 more
TL;DR: New dihydrobenzopyran, thiochroman, tetrahydroquinoleine and tetrahedronaphthalene derivatives and their use in anti-cancer therapy with the general formula (I) were described in this paper.
Journal Article
3-Methyl-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1,1-dioxide
TL;DR: In this paper, the title compound, C7H7N302S, was compared with diazoxide, an antihypertensive agent, from a structural and pharmacological point of view, and it was shown that the 4H (rather than 2H) tautomeric form is preferentially adopted by this pyridothiadiazine derivative in the solid state.
Patent
Dihydrobenzopyran, thiochroman, tetrahydroquinoleine and tetrahydronaphthalene derivatives and their use in anti-cancer therapy
Eric Goffin,Pascal De Tullio,Xavier Florence,Bernard Pirotte,Bernard Rogister,Delphine Lamoral-Theys,Robert Kiss,Florence Lefranc +7 more
TL;DR: New dihydrobenzopyran, thiochroman, tetrahydroquinoleine and tetrahedronaphthalene derivatives and their use in anti-cancer therapy with the general formula as discussed by the authors.
Patent
Cyclodextrin and budesonide derivative compositions and methods
TL;DR: In this paper, the use of validated 1H NMR analysis for the detection and quantification of cyclodextrins directly in pharmaceutical formulations without any extraction or separation steps for liquid formulations.