P
Patrick H. Corran
Researcher at University of London
Publications - 60
Citations - 3651
Patrick H. Corran is an academic researcher from University of London. The author has contributed to research in topics: Malaria & Plasmodium falciparum. The author has an hindex of 27, co-authored 60 publications receiving 3370 citations. Previous affiliations of Patrick H. Corran include The Hertz Corporation & National Institute for Biological Standards and Control.
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Journal ArticleDOI
Recombinant Human Albumin as a Stabilizer for Biological Materials and for the Preparation of International Reference Reagents
Edward Tarelli,Anthony R. Mire-Sluis,Helen Ann Tivnann,Barbara Bolgiano,Dennis T. Crane,Christopher K. Gee,Xavier Lemercinier,Margareth L. Athayde,Nicholas Sutcliffe,Patrick H. Corran,B. Rafferty +10 more
TL;DR: Recombinant human albumin expressed in Saccharomyces cerevisiae was compared with native human serum albumin in its physicochemical properties and in its use as a stabilizer in lyophilized preparations of thyroid- Stimulating hormone, interleukin 15 and granulocyte colony-stimulating factor.
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The Fine Specificity, but Not the Invasion Inhibitory Activity, of 19-Kilodalton Merozoite Surface Protein 1-Specific Antibodies Is Associated with Resistance to Malarial Parasitemia in a Cross-Sectional Survey in The Gambia
Patrick H. Corran,Patrick H. Corran,Rebecca A. O'Donnell,Jim Todd,Chairat Uthaipibull,Anthony A. Holder,Brendan S. Crabb,Eleanor M. Riley +7 more
TL;DR: In this article, the authors analyzed prevalence, fine specificity, and 19kilodalton merozoite surface protein 1 (MSP-119)-specific erythrocyte invasion inhibitory activity of antibodies to MSP119 and found no significant association between any of these parameters and prevalence or density of malarial parasitemia.
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Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children.
Philip Bejon,Philip Bejon,Jackie Cook,Elke S. Bergmann-Leitner,Ally Olotu,John Lusingu,John Lusingu,Jedidah Mwacharo,Johan Vekemans,Patricia Njuguna,Amanda J. Leach,Marc Lievens,Sheetij Dutta,Lorenz von Seidlein,Barbara Savarese,Tonya Villafana,Martha M. Lemnge,Joe Cohen,Kevin Marsh,Kevin Marsh,Patrick H. Corran,Patrick H. Corran,Evelina Angov,Eleanor M. Riley,Chris Drakeley +24 more
TL;DR: Vaccination with RTS,S/AS01E reduces exposure to blood-stage parasites and, thus, reduces anti-merozoite antigen antibody concentrations, but these antibodies were not correlates of clinical immunity to malaria.
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Interaction of malaria with a common form of severe thalassemia in an Asian population
Angela O’Donnell,Anuja Premawardhena,M. Arambepola,R. Samaranayake,Stephen Allen,Tim E. A. Peto,C A Fisher,Jackie Cook,Patrick H. Corran,Nancy F. Olivieri,David J. Weatherall +10 more
TL;DR: Patients with HbE β thalassemia may be more prone to malaria, particularly P. vivax, which is reflected in their clinical severity, and further studies of its interaction with HBE βThalassemi and related diseases are required urgently.
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Serology describes a profile of declining malaria transmission in Farafenni, The Gambia
Lotus L. van den Hoogen,Jamie T. Griffin,Jackie Cook,Nuno Sepúlveda,Nuno Sepúlveda,Patrick H. Corran,David J. Conway,Paul Milligan,Muna Affara,Stephen Allen,Carla Proietti,Serign J. Ceesay,Geoffrey A. T. Targett,Umberto D'Alessandro,Umberto D'Alessandro,Brian Greenwood,Eleanor M. Riley,Chris Drakeley +17 more
TL;DR: This analysis shows accurate reconstruction of historical malaria transmission patterns in the Farafenni area using anti-malarial antibody responses, demonstrating congruence between serological measures, and conventional clinical and parasitological measures suggests broader utility for serology in monitoring and evaluation of malaria transmission.