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Paul B. Fisher
Researcher at Virginia Commonwealth University
Publications - 486
Citations - 35304
Paul B. Fisher is an academic researcher from Virginia Commonwealth University. The author has contributed to research in topics: Cancer & Cancer cell. The author has an hindex of 80, co-authored 449 publications receiving 31149 citations. Previous affiliations of Paul B. Fisher include Discovery Institute & Columbia University Medical Center.
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Journal ArticleDOI
Multi-nucleated cells use ROS to induce breast cancer chemo-resistance in vitro and in vivo
Aditya Parekh,Subhayan Das,Sheetal Parida,Chandan Kanta Das,Debabrata Dutta,Sanjaya K. Mallick,Pei Hsun Wu,B. N. Prashanth Kumar,Rashmi Bharti,Goutam Dey,Kacoli Banerjee,Shashi Rajput,Deblina Bharadwaj,Ipsita Pal,Kaushik Kumar Dey,Y. Rajesh,Bikash Chandra Jena,Angana Biswas,Payel Banik,Anjan K. Pradhan,Swadesh K. Das,Amit Das,Santanu Dhara,Paul B. Fisher,Denis Wirtz,Gordon B. Mills,Mahitosh Mandal +26 more
TL;DR: It is shown that oxidatively stressed MNCs induce chemo-resistance in vitro and in vivo by secreting VEGF and MIF, and that the ROS-HIF-1α signaling axis is very crucial in regulation of chemo -resistance by M NCs.
Journal ArticleDOI
Obatoclax and lapatinib interact to induce toxic autophagy through NOXA.
TL;DR: The data argue that lapatinib and obatoclax-induced toxic autophagy is due to impaired autophagic degradation, and this disturbance of autophagosome flux leads to an accumulation of toxic proteins and loss of mitochondrial function.
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Novel Role of MDA-9/Syntenin in Regulating Urothelial Cell Proliferation by Modulating EGFR Signaling
Santanu Dasgupta,Mitchell E. Menezes,Swadesh K. Das,Luni Emdad,Aleksandar Janjic,Shilpa Bhatia,Nitai D. Mukhopadhyay,Chunbo Shao,Devanand Sarkar,Paul B. Fisher +9 more
TL;DR: The findings indicate that MDA-9/Syntenin might provide an attractive target for developing detection, monitoring, and therapeutic strategies for managing UCC.
Journal Article
Regulation of class II MHC gene expression by interferons: insights into the mechanism of action of interferon (review).
TL;DR: The structural organization of the 5' flanking regions of the MHC genes is discussed, with special emphasis on class II genes, and the implications of these data for the transcriptional regulation of these and of other interferon inducible genes.
Journal Article
Immunochemical analysis of the modulation of human melanoma-associated antigens by DNA recombinant immune interferon
Patrizio Giacomini,Imberti L,Adriano Aguzzi,Paul B. Fisher,Giorgio Trinchieri,Soldano Ferrone +5 more
TL;DR: The effect of recombinant immune interferon (IFN-gamma) on the synthesis, expression, and shedding of a cytoplasmic melanoma-associated antigen (MAA) and of the membrane-bound high m.w. MAA (HMW-MAA), 115K MAA, and 100K M AA has been investigated.