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Paul B. Fisher

Researcher at Virginia Commonwealth University

Publications -  486
Citations -  35304

Paul B. Fisher is an academic researcher from Virginia Commonwealth University. The author has contributed to research in topics: Cancer & Cancer cell. The author has an hindex of 80, co-authored 449 publications receiving 31149 citations. Previous affiliations of Paul B. Fisher include Discovery Institute & Columbia University Medical Center.

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Journal ArticleDOI

Polynucleotide phosphorylase: an evolutionary conserved gene with an expanding repertoire of functions.

TL;DR: A global perspective on the structure and function of PNPase is provided and a focus on hPNPase old-35 in the contexts of differentiation and senescence is focused on.
Book ChapterDOI

EGFR: An essential receptor tyrosine kinase-regulator of cancer stem cells.

TL;DR: It may be of value to simultaneously combine multiple EGFR inhibitors or use EGFR inhibitor with regulators of other important cancer phenotype regulating molecules, such as STAT3, or involved in important processes such as DNA repair.
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The development of MDA-7/IL-24 as a cancer therapeutic

TL;DR: The cytokine melanoma differentiation associated gene 7 (mda-7) was identified by subtractive hybridization as a protein whose expression increased during the induction of terminal differentiation, and that was either not expressed or was present at low levels in tumor cells compared to non-transformed cells.
Book ChapterDOI

AEG-1/MTDH/LYRIC, the beginning: initial cloning, structure, expression profile, and regulation of expression.

TL;DR: AEG-1/MTDH/LYRIC is a pleiotropic protein that can localize in the cell membrane, cytoplasm, endoplasmic reticulum (ER), nucleus, and nucleolus, and contributes to diverse signaling pathways such as PI3K-AKT, NF-κB, MAPK and Wnt as discussed by the authors.
Journal ArticleDOI

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Daniel J. Klionsky, +2522 more
- 01 Jan 2016 - 
TL;DR: Author(s): Klionsky, DJ; Abdelmohsen, K; Abe, A; Abedin, MJ; Abeliovich, H; A Frozena, AA; Adachi, H, Adeli, K, Adhihetty, PJ; Adler, SG; Agam, G; Agarwal, R; Aghi, MK; Agnello, M; Agostinis, P; Aguilar, PV; Aguirre-Ghis