P
Pauline N. Ward
Researcher at University of Glasgow
Publications - 5
Citations - 2225
Pauline N. Ward is an academic researcher from University of Glasgow. The author has contributed to research in topics: Gene & FASTA format. The author has an hindex of 4, co-authored 4 publications receiving 2102 citations.
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Journal ArticleDOI
The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease
Najib M. El-Sayed,Peter J. Myler,Peter J. Myler,Daniella Castanheira Bartholomeu,Daniel Nilsson,Gautam Aggarwal,Anh-Nhi Tran,Elodie Ghedin,Elizabeth A. Worthey,Arthur L. Delcher,Gaëlle Blandin,Scott J. Westenberger,Elisabet Caler,Gustavo C. Cerqueira,Carole Branche,Brian J. Haas,Atashi Anupama,Erik Arner,Lena Åslund,Philip Attipoe,Esteban J. Bontempi,Frédéric Bringaud,Peter Burton,Eithon Cadag,David A. Campbell,Mark Carrington,Jonathan Crabtree,Hamid Darban,José Franco da Silveira,Pieter J. de Jong,Kimberly Edwards,Paul T. Englund,Gholam Fazelina,Tamara Feldblyum,Marcela Ferella,Alberto C.C. Frasch,Keith Gull,David Horn,Lihua Hou,Yiting Huang,Ellen Kindlund,Michele M. Klingbeil,Sindy Kluge,Hean Koo,Daniela R. Lacerda,Mariano J. Levin,Hernan Lorenzi,Tin Louie,Carlos Renato Machado,Richard McCulloch,Alan McKenna,Yumi Mizuno,Jeremy C. Mottram,Siri Nelson,Stephen Ochaya,Kazutoyo Osoegawa,Grace Pai,Marilyn Parsons,Marilyn Parsons,Martin Pentony,Ulf Pettersson,Mihai Pop,José Luis Ramírez,Joel Rinta,Laura Robertson,Steven L. Salzberg,Daniel O. Sánchez,Amber Seyler,Reuben Sunil Kumar Sharma,Jyoti Shetty,Anjana J. Simpson,Ellen Sisk,Martti T. Tammi,Martti T. Tammi,Rick L. Tarleton,Santuza M. R. Teixeira,Susan Van Aken,Christy Vogt,Pauline N. Ward,Bill Wickstead,Jennifer R. Wortman,Owen White,Claire M. Fraser,Kenneth Stuart,Kenneth Stuart,Björn Andersson +85 more
TL;DR: Although the Tritryp lack several classes of signaling molecules, their kinomes contain a large and diverse set of protein kinases and phosphatases; their size and diversity imply previously unknown interactions and regulatory processes, which may be targets for intervention.
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Protein kinases of the human malaria parasite Plasmodium falciparum: the kinome of a divergent eukaryote
TL;DR: An exhaustive analysis of the P. falciparum genomic database (PlasmoDB) aimed at identifying and classifying all ePKs in this organism found that profound divergences between the kinome of malaria parasites and that of yeast or mammalian cells are reflected.
Journal ArticleDOI
Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi.
TL;DR: A genome-wide analysis of protein kinases of these three trypanosomatids reveals a large set of PKs, comprising approximately 2% of each genome, suggesting a key role for phosphorylation in parasite biology.
Journal ArticleDOI
VSGdb: a database for trypanosome variant surface glycoproteins, a large and diverse family of coiled coil proteins
Lucio Marcello,Suraj Menon,Suraj Menon,Pauline N. Ward,Jonathan M. Wilkes,Nicola G. Jones,Mark Carrington,J. David Barry +7 more
TL;DR: VSGdb is a freely available, web-based platform enabling easy retrieval, via various filters, of sets of VSGs that will enable detailed analysis of a number of general and trypanosome-specific questions, regarding protein structure potential, epitope variability, sequence evolution and recombination events.
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Data 4 Climate Action Edinburgh
TL;DR: Data 4 Climate Action Edinburgh (D4CAE) as discussed by the authors is a group of volunteers who donate their time and skills with data to support climate action and biodiversity in and around Edinburgh.