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Peng Liu

Researcher at University of Pittsburgh

Publications -  178
Citations -  11414

Peng Liu is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Catalysis & Enantioselective synthesis. The author has an hindex of 57, co-authored 170 publications receiving 9113 citations. Previous affiliations of Peng Liu include Laboratory of Molecular Biology & Massachusetts Institute of Technology.

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Genome-wide Profiling of 5-Formylcytosine Reveals Its Roles in Epigenetic Priming

TL;DR: It is shown that the genomic locations of 5fC can be determined by coupling chemical reduction with biotin tagging, and roles of active 5mC/5hmC oxidation and TDG-mediated demethylation in epigenetic tuning at regulatory elements are revealed.
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Conversion of amides to esters by the nickel-catalysed activation of amide C-N bonds

TL;DR: It is demonstrated that amide carbon–nitrogen bonds can be activated and cleaved using nickel catalysts and is expected to lead to the further use of amides in the construction of carbon–heteroatom or carbon–carbon bonds using non-precious-metal catalysis.
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Mechanism of Photoinduced Metal-Free Atom Transfer Radical Polymerization: Experimental and Computational Studies.

TL;DR: A deeper understanding of the chemical processes of metal-free ATRP is provided that can aid the design of better catalytic systems and elucidates several important common pathways involved in synthetically useful organic reactions catalyzed by photoredox catalysts.
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Computational explorations of mechanisms and ligand-directed selectivities of copper-catalyzed Ullmann-type reactions.

TL;DR: In this article, the authors investigated ligand-directed selectivities in Ullmann-type coupling reactions of methanol and methylamine with iodobenzene by β-diketone-and 1,10-phenanthroline-ligated CuI complexes.
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Palladium-catalyzed meta-selective C-H bond activation with a nitrile-containing template: computational study on mechanism and origins of selectivity.

TL;DR: Structural and distortion energy analysis of the transition states revealed significant effects of distortions of the template on mechanism and regioselectivity, which provided hints for further developments of new templates.