P
Peter Simmonds
Researcher at University of Oxford
Publications - 857
Citations - 69113
Peter Simmonds is an academic researcher from University of Oxford. The author has contributed to research in topics: Hepatitis C virus & Virus. The author has an hindex of 131, co-authored 823 publications receiving 62953 citations. Previous affiliations of Peter Simmonds include John Radcliffe Hospital & Edinburgh Royal Infirmary.
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Journal ArticleDOI
Functional Analysis of RNA Structures Present at the 3′ Extremity of the Murine Norovirus Genome: the Variable Polypyrimidine Tract Plays a Role in Viral Virulence
Dalan Bailey,Ioannis Karakasiliotis,Surender Vashist,Liliane Man Wah Chung,Jivan Reese,Nora McFadden,Alicia Benson,Felix Yarovinsky,Peter Simmonds,Ian Goodfellow +9 more
TL;DR: This work highlights how, like with other positive-strand RNA viruses, RNA structures present at the termini of the norovirus genome play important roles in virus replication and virulence.
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HIV antigen and antibody detection: variable responses to infection in the Edinburgh haemophiliac cohort
Peter Simmonds,F A L Lainson,R. J. G. Cuthbert,C M Steel,John F. Peutherer,Christopher A. Ludlam +5 more
TL;DR: Although amounts of total antibody to HIV and of antibodies to envelope proteins rose continuously during the two years of the study, amounts of antibody to the core protein were variable and tended to decline in patients who became symptomatic, and much of the variability in the course of infection with HIV must represent the differences in the susceptibility of the patients to infection.
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Parenteral transmission of the novel human parvovirus PARV4.
TL;DR: Predominantly parenteral routes of transmission of PARV4 were demonstrated by infection restricted to injection drug users and persons with hemophilia and absence of infection in homosexual men with AIDS and low-risk controls.
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Reconciling reported and unreported HFC emissions with atmospheric observations
Mark Lunt,Matthew Rigby,Anita L. Ganesan,Alistair J. Manning,Ronald G. Prinn,Simon O'Doherty,Jens Mühle,Christina M. Harth,Peter K. Salameh,Tim Arnold,Ray F. Weiss,Takuya Saito,Yoko Yokouchi,Paul B. Krummel,L. Paul Steele,Paul J. Fraser,Shanlan Li,Sunyoung Park,Stefan Reimann,Martin K. Vollmer,Chris Rene Lunder,Ove Hermansen,Norbert Schmidbauer,Michela Maione,Jgor Arduini,Dickon Young,Peter Simmonds +26 more
TL;DR: In this article, the authors infer global and regional emissions of five of the most abundant hydrofluorocarbons (HFCs) using atmospheric measurements from the Advanced Global Atmospheric Gases Experiment and the National Institute for Environmental Studies, Japan, networks.
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Does drug abuse alter microglial phenotype and cell turnover in the context of advancing HIV infection
TL;DR: The combination of drug abuse and HIV infection has a greater deleterious effect on the brain than either individual insult on its own.