P
Peter Simmonds
Researcher at University of Oxford
Publications - 857
Citations - 69113
Peter Simmonds is an academic researcher from University of Oxford. The author has contributed to research in topics: Hepatitis C virus & Virus. The author has an hindex of 131, co-authored 823 publications receiving 62953 citations. Previous affiliations of Peter Simmonds include John Radcliffe Hospital & Edinburgh Royal Infirmary.
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Within-host genomics of SARS-CoV-2
Katrina A. Lythgoe,Matthew Hall,Luca Ferretti,M de Cesare,G MacIntyre-Cockett,Amy Trebes,Monique Andersson,Newton Otecko,Emma L. Wise,Emma L. Wise,Nathan Moore,Jessica Lynch,Stephen P. Kidd,Nick Cortes,Matilde Mori,Rebecca Williams,Gabrielle Vernet,Anita Justice,Angie Green,Samuel M. Nicholls,A Ansari,Lucie Abeler-Dörner,C Moore,T Peto,David W Eyre,David W Eyre,Robert Shaw,Peter Simmonds,David Buck,John A. Todd,Thomas R. Connor,A da Silva Filipe,James Shepherd,E. Thomson,David Bonsall,Christophe Fraser,Tanya Golubchik +36 more
TL;DR: It is shown that SARS-CoV-2 infections are characterised by low levels of within-host diversity across the entire viral genome, with evidence of strong evolutionary constraint in Spike, a key target of vaccines and antibody-based therapies.
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PARV4: An Emerging Tetraparvovirus
TL;DR: This work aims to provide real-time information about the immune checkpoints in the immune response to pathogen infection and its role in disease and disease progression.
Journal ArticleDOI
The genetic diversification of the HIV type 1 gag p17 gene in patients infected from a common source
P. Kasper,Peter Simmonds,K. E. Schneweis,Rolf Kaiser,Bertfried Matz,J. Oldenburg,H.-H. Brackmann,Edward C. Holmes +7 more
TL;DR: An evolutionary analysis was undertaken of HIV-1 gag p17 sequences taken from a small cohort of hemophilia B patients infected from a common batch of clotting factor concentrate, suggesting that the infecting batch also contained little sequence variation.
Journal ArticleDOI
Frequency, viral loads, and serotype identification of enterovirus infections in Scottish blood donors.
TL;DR: A large‐scale survey of frequency and levels of viremia in blood donors was conducted to investigate the threat to blood safety from enteroviruses.
Journal ArticleDOI
Enhancement of immunohistochemical detection of HIV-1 p24 antigen in brain by tyramide signal amplification
Padraig Strappe,Ting Huei Wang,Chris Anne McKenzie,Suzanne Lowrie,Peter Simmonds,Jeanne E. Bell +5 more
TL;DR: Human immunodeficiency virus type 1 (HIV-1) infection of the brain has been demonstrated in formalin fixed, paraffin embedded post-mortem brain tissue (PM) by chromogenic immunohistochemistry for the HIV p24 antigen by TSA enhanced immunofluorescence.