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Peter Simmonds

Researcher at University of Oxford

Publications -  857
Citations -  69113

Peter Simmonds is an academic researcher from University of Oxford. The author has contributed to research in topics: Hepatitis C virus & Virus. The author has an hindex of 131, co-authored 823 publications receiving 62953 citations. Previous affiliations of Peter Simmonds include John Radcliffe Hospital & Edinburgh Royal Infirmary.

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The association of recombination events in the founding and emergence of subgenogroup evolutionary lineages of human enterovirus 71.

TL;DR: Intriguingly, recombination events occurred as a founding event of most subgenogroups immediately preceding their lineage expansion and global emergence, suggesting the possibility that recombination contributed to their subsequent spread through improved fitness requires further biological and immunological characterization.
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Direct identification of human enterovirus serotypes in cerebrospinal fluid by amplification and sequencing of the VP1 region.

TL;DR: The availability of a simple and rapid method for identification of serotypes and individual HEV strains or clusters directly from CSF will be of substantial value in surveillance, understanding more about serotype-associated differences in disease and monitoring the global spread of pathogenic variants such as enterovirus 71.
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Detection of Hepatitis B Virus Infection in Wild-Born Chimpanzees (Pan troglodytes verus): Phylogenetic Relationships with Human and Other Primate Genotypes

TL;DR: Strong evidence is provided for a chimpanzee-specific genotype of HBV which circulates in nature and adds to the recent evidence for infection in the wild of other Old and New World primates with species-specific variants ofHBV.
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Bioinformatic and Physical Characterizations of Genome-Scale Ordered RNA Structure in Mammalian RNA Viruses

TL;DR: Bioinformatic and physical characterization methods both identified fundamental differences in the configurations of viral genomic RNA that may modify their interactions with host cell defenses and their ability to persist.