P
Philippe Deloron
Researcher at University of Paris
Publications - 288
Citations - 8720
Philippe Deloron is an academic researcher from University of Paris. The author has contributed to research in topics: Plasmodium falciparum & Malaria. The author has an hindex of 47, co-authored 282 publications receiving 8176 citations. Previous affiliations of Philippe Deloron include Texas A&M University & Institut Français.
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Journal ArticleDOI
Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: a systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic response using individual patient data
Elizabeth A. Ashley,Francesca T. Aweeka,Karen I. Barnes,Quique Bassat,Steffen Borrmann,Steffen Borrmann,Prabin Dahal,Prabin Dahal,Tme Davis,Philippe Deloron,Mey Bouth Denis,Abdoulaye Djimde,Jean-François Faucher,Blaise Genton,Blaise Genton,Philippe J Guerin,Kamal Hamed,Eva Maria Hodel,Eva Maria Hodel,Liusheng Huang,Jullien,Harin Karunajeewa,Harin Karunajeewa,Kiechel,Poul-Erik Kofoed,Gilbert Lefèvre,Niklas Lindegardh,Kevin Marsh,Kevin Marsh,Andreas Mårtensson,Mayfong Mayxay,Mayfong Mayxay,Rose McGready,C Moreira,Paul N. Newton,Billy Ngasala,François Nosten,Christian Nsanzabana,Christian Nsanzabana,Sunil Parikh,Ric N. Price,Pascal Ringwald,Lars Rombo,Lars Rombo,Birgit Schramm,Carol Hopkins Sibley,Kasia Stepniewska,Johan Ursing,Michèle van Vugt,Michèle van Vugt,Nicholas J. White,Lesley Workman +51 more
TL;DR: Higher, more frequent, or prolonged dosage regimens should now be evaluated in very young children, particularly if malnourished, and in patients with hyperparasitemia, as well as patients in very low transmission intensity areas with emerging parasite resistance.
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Interferon-γ Responses Are Associated with Resistance to Reinfection with Plasmodium falciparum in Young African Children
Adrian J. F. Luty,Bertrand Lell,Ruprecht Schmidt-Ott,Leopold Gustave Lehman,Doris Luckner,Bernhard Greve,Peter Matousek,Klaus Herbich,Daniela Schmid,Florence Migot-Nabias,Philippe Deloron,Ruth S. Nussenzweig,Peter G. Kremsner +12 more
TL;DR: Differences in the Th1/Th2 cytokine balance may be linked to the ability to control parasite multiplication in these young children, helping to explain the marked differences observed in both susceptibility to infection as well as in clinical presentation.
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High Level of var2csa Transcription by Plasmodium falciparum Isolated from the Placenta
Nicaise Tuikue Ndam,Ali Salanti,Gwladys Bertin,Madeleine Dahlbäck,Nadine Fievet,Louise Turner,Alioune Gaye,Thor G. Theander,Philippe Deloron +8 more
TL;DR: It is shown that placental P. falciparum isolates highly transcribed var2csa but not var1csa, which supports the idea that VAR2CSA plays a crucial role in PAM and strengthens the rationale for the development of VAR 2CSA-based vaccines.
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High uptake of Intermittent Preventive Treatment of malaria in pregnancy is associated with improved birth weight among pregnant women in Ghana
Isabella A. Quakyi,Isabella A. Quakyi,Bernard Tornyigah,Bernard Tornyigah,Pascal Houzé,Pascal Houzé,Pascal Houzé,Kwadwo A. Kusi,Nathaniel Coleman,Guillaume Escriou,Amos Laar,Michel Cot,Julius N. Fobil,Gloria Quansah Asare,Philippe Deloron,Abraham K. Anang,Gilles Cottrell,Michael F. Ofori,Nicaise Tuikue Ndam,Nicaise Tuikue Ndam +19 more
TL;DR: The new IPTp policy is well implemented and well utilised by women in the sites considered in this study and translates to the improved birth weight observed, confirming the interest and the clinical benefit expected from this policy change.
Journal ArticleDOI
Maternal placental infection with Plasmodium falciparum and malaria morbidity during the first 2 years of life
J Y Le Hesran,Michel Cot,P. Personne,N. Fievet,B. Dubois,B. Dubois,M. Beyeme,C. Boudin,Philippe Deloron +8 more
TL;DR: Malarial infection of the placenta seems to result in a higher susceptibility of infants to the parasite, and a better understanding of the involved mechanisms may have important implications for the development of malaria control strategies.