J
Jean-François Faucher
Researcher at Institut de recherche pour le développement
Publications - 33
Citations - 901
Jean-François Faucher is an academic researcher from Institut de recherche pour le développement. The author has contributed to research in topics: Malaria & Leptospirosis. The author has an hindex of 10, co-authored 33 publications receiving 834 citations. Previous affiliations of Jean-François Faucher include Paris Descartes University.
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Journal ArticleDOI
Artemether-lumefantrine treatment of uncomplicated Plasmodium falciparum malaria: a systematic review and meta-analysis of day 7 lumefantrine concentrations and therapeutic response using individual patient data
Elizabeth A. Ashley,Francesca T. Aweeka,Karen I. Barnes,Quique Bassat,Steffen Borrmann,Steffen Borrmann,Prabin Dahal,Prabin Dahal,Tme Davis,Philippe Deloron,Mey Bouth Denis,Abdoulaye Djimde,Jean-François Faucher,Blaise Genton,Blaise Genton,Philippe J Guerin,Kamal Hamed,Eva Maria Hodel,Eva Maria Hodel,Liusheng Huang,Jullien,Harin Karunajeewa,Harin Karunajeewa,Kiechel,Poul-Erik Kofoed,Gilbert Lefèvre,Niklas Lindegardh,Kevin Marsh,Kevin Marsh,Andreas Mårtensson,Mayfong Mayxay,Mayfong Mayxay,Rose McGready,C Moreira,Paul N. Newton,Billy Ngasala,François Nosten,Christian Nsanzabana,Christian Nsanzabana,Sunil Parikh,Ric N. Price,Pascal Ringwald,Lars Rombo,Lars Rombo,Birgit Schramm,Carol Hopkins Sibley,Kasia Stepniewska,Johan Ursing,Michèle van Vugt,Michèle van Vugt,Nicholas J. White,Lesley Workman +51 more
TL;DR: Higher, more frequent, or prolonged dosage regimens should now be evaluated in very young children, particularly if malnourished, and in patients with hyperparasitemia, as well as patients in very low transmission intensity areas with emerging parasite resistance.
Journal ArticleDOI
The effect of dose on the antimalarial efficacy of artemether-lumefantrine: a systematic review and pooled analysis of individual patient data.
Nicholas M. Anstey,Ric N. Price,Tme Davis,Harin Karunajeewa,Ivo Mueller,Umberto D'Alessandro,Achille Massougbodji,Frederic Nikiema,Jean-Bosco Ouédraogo,Halidou Tinto,Issaka Zongo,Albert Same-Ekobo,M Kone,H Menan,AO Toure,William Yavo,Poul-Erik Kofoed,Bereket Alemayehu,Daddi Jima,Elisabeth Baudin,Emmanuelle Espie,Carolyn Nabasumba,Loretxu Pinoges,Birgit Schramm,Michel Cot,Philippe Deloron,Jean-François Faucher,Jean-Paul Guthmann,Bertrand Lell,Steffen Borrmann,George O. Adjei,J Ursing,Emiliana Tjitra,Kevin Marsh,Judy Peshu,Elizabeth Juma,Bernhards Ogutu,Sabah A. Omar,Patrick Sawa,Ambrose O. Talisuna,Maniphone Khanthavong,M Mayxay,Paul N. Newton,Patrice Piola,Abdoulaye Djimde,Ogobara K. Doumbo,Bakary Fofana,Issaka Sagara,Quique Bassat,Raquel González,Clara Menéndez,Frank Smithuis,Teun Bousema,Piet A. Kager,P. F. Mens,Hdfh Schallig,I Van den Broek,M. van Vugt,Maman Laminou Ibrahim,Catherine O. Falade,Martin M Meremikwu,José Pedro Gil,Corine Karema,Ba,Babacar Faye,Oumar Faye,Gaye O,Jean Louis Ndiaye,Mbaye Pene,Doudou Sow,K Sylla,Rck Tine,Louis K. Penali,Karen I. Barnes,Lesley Workman,Angeles Lima,Ishag Adam,Nahla B Gadalla,Efm Malik,Anders Björkman,Andreas Mårtensson,Billy Ngasala,Lars Rombo,P Aliu,Stephan Duparc,Scott G. Filler,Blaise Genton,Eva Maria Hodel,Piero Olliaro,S Abdulla,Erasmus Kamugisha,Zulfiqarali Premji,Seif Shekalaghe,Elizabeth A. Ashley,Verena I. Carrara,Rose McGready,François Nosten,Abul Faiz,Sue J. Lee,Nicholas J. White,Arjen M. Dondorp,Jeff Smith,Joel Tarning,Jane Achan,Hasifa Bukirwa,Adoke Yeka,Emmanuel Arinaitwe,Sarah G. Staedke,Kamya,Fred Kironde,Chris Drakeley,Mary C. Oguike,Colin J. Sutherland,Francesco Checchi,Prabin Dahal,Jennifer A. Flegg,Philippe J Guerin,Clarissa Moreira,Christian Nsanzabana,Carol Hopkins Sibley,Kasia Stepniewska,Peter W. Gething,Si Hay,Brian Greenwood,Stephen A. Ward,P. A. Winstanley,Grant Dorsey,Bryan Greenhouse,P. Rosenthal,Anastasia Grivoyannis,Kamal Hamed,J Hwang,PS Kachur,Michael Nambozi +133 more
TL;DR: The recommended dose of artemether-lumefantrine provides reliable efficacy in most patients with uncomplicated malaria, however, therapeutic efficacy was lowest in young children from Asia and young underweight children from Africa; a higher dose regimen should be assessed in these groups.
Journal ArticleDOI
PfHRP2 and PfLDH antigen detection for monitoring the efficacy of artemisinin-based combination therapy (ACT) in the treatment of uncomplicated falciparum malaria
TL;DR: Although both RDTs are as sensitive as microscopy in detecting true malaria cases, the Pf HRP2 RDT had very low specificity during follow-up until day 28, while the Pf LDH test could be used to detect failures and, therefore, to assess anti-malarial efficacy.
Journal ArticleDOI
Comparison of Sulfadoxine‐Pyrimethamine, Unsupervised Artemether‐Lumefantrine, and Unsupervised Artesunate‐Amodiaquine Fixed‐Dose Formulation for Uncomplicated Plasmodium falciparum Malaria in Benin: A Randomized Effectiveness Noninferiority Trial
Jean-François Faucher,Agnès Aubouy,Adicat Adeothy,Gilles Cottrell,Justin Doritchamou,Bernard Gourmel,Pascal Houzé,Hortense Kossou,Hyacinthe Amedome,Achille Massougbodji,Michel Cot,Philippe Deloron +11 more
TL;DR: This was the first trial, to the authors' knowledge, to compare unsupervised AL with unsuper supervised ASAQ fixed-dose formulation; both treatments provided high PCR-adjusted day 28 effectiveness rates.
Journal ArticleDOI
The management of leptospirosis
TL;DR: Adjunctive therapies proposed in the management of severe forms of leptospirosis and Jarisch–Herxheimer reactions, are reviewed.