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Phillip A. Gall
Researcher at Stanford University
Publications - 5
Citations - 252
Phillip A. Gall is an academic researcher from Stanford University. The author has contributed to research in topics: Respiratory tract & Motile cilium. The author has an hindex of 3, co-authored 5 publications receiving 138 citations.
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Journal ArticleDOI
ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs.
Ivan T. Lee,Tsuguhisa Nakayama,Chien-Ting Wu,Yury Goltsev,Sizun Jiang,Phillip A. Gall,Chun Kang Liao,Liang Chun Shih,Christian M. Schürch,David R. McIlwain,Pauline Chu,Nicole A. Borchard,David Zarabanda,Sachi S. Dholakia,Angela Yang,Dayoung Kim,Han Chen,Tomoharu Kanie,Chia-Der Lin,Ming Hsui Tsai,Katie M. Phillips,Raymond Kim,Jonathan B. Overdevest,Jonathan B. Overdevest,Matthew A. Tyler,Matthew A. Tyler,Carol H. Yan,Carol H. Yan,Chih Feng Lin,Yi Tsen Lin,Da Tian Bau,Gregory J. Tsay,Zara M. Patel,Yung An Tsou,Alexandar Tzankov,Matthias S. Matter,Chih Jaan Tai,Te-Huei Yeh,Peter H. Hwang,Garry P. Nolan,Jayakar V. Nayak,Peter K. Jackson +41 more
TL;DR: The discovery that the ACE2 receptor protein robustly localizes within the motile cilia of airway epithelial cells, which likely represents the initial or early subcellular site of SARS-CoV-2 viral entry during host respiratory transmission, is reported.
Posted ContentDOI
Robust ACE2 protein expression localizes to the motile cilia of the respiratory tract epithelia and is not increased by ACE inhibitors or angiotensin receptor blockers
Ivan T. Lee,Tsuguhisa Nakayama,Chien-Ting Wu,Yury Goltsev,Sizun Jiang,Phillip A. Gall,Chun-Kang Liao,Liang-Chun Shih,Christian M. Schürch,David R. McIlwain,Pauline Chu,Nicole A. Borchard,David Zarabanda,Sachi S. Dholakia,Angela Yang,Dayoung Kim,Tomoharu Kanie,Chia-Der Lin,Ming Hsui Tsai,Katie M. Phillips,Raymond Kim,Jonathan B. Overdevest,Matthew A. Tyler,Carol H. Yan,Chih-Feng Lin,Yi-Tsen Lin,Da Tian Bau,Gregory J. Tsay,Zara M. Patel,Yung An Tsou,Chih Jaan Tai,Te-Huei Yeh,Peter H. Hwang,Garry P. Nolan,Jayakar V. Nayak,Peter K. Jackson +35 more
TL;DR: Investigation of the expression and subcellular localization of the SARS-CoV-2 receptor, angiotensin-converting enzyme 2 (ACE2), within the upper (nasal) and lower (pulmonary) respiratory tracts of healthy human donors found no evidence that the use of angiotENSin- Converting enzyme inhibitors (ACEI) or ang Elliotensin II receptor blockers (ARBs) increases ACE2 protein expression.
Journal ArticleDOI
Leading-Brand Advertisement of Quitting Smoking Benefits for E-Cigarettes.
TL;DR: Among leading e-cigarette advertisers, cessation themes are prevalent with implicit messaging predominating over explicit quit claims, which can help the Food and Drug Administration clarify whether tobacco products should be regulated as drugs with therapeutic purpose or as recreational products.
Journal ArticleDOI
Determinants of SARS-CoV-2 entry and replication in airway mucosal tissue and susceptibility in smokers.
Tsuguhisa Nakayama,Tsuguhisa Nakayama,Ivan T. Lee,Sizun Jiang,Sizun Jiang,Matthias S. Matter,Carol H. Yan,Jonathan B. Overdevest,Chien-Ting Wu,Yury Goltsev,Liang Chun Shih,Chun-Kang Liao,Bokai Zhu,Yunhao Bai,Peter V. Lidsky,Yinghong Xiao,David Zarabanda,Angela Yang,Meena Easwaran,Christian M. Schürch,Pauline Chu,Han Chen,Anna K. Stalder,David R. McIlwain,Nicole A. Borchard,Phillip A. Gall,Sachi S. Dholakia,Wei Le,Le Xu,Chih Jaan Tai,Te-Huei Yeh,Elizabeth Erickson-DiRenzo,Jason M. Duran,Kirsten D. Mertz,Peter H. Hwang,Jasmin D. Haslbauer,Peter K. Jackson,Thomas Menter,Raul Andino,Peter Canoll,Adam S. DeConde,Zara M. Patel,Alexandar Tzankov,Garry P. Nolan,Jayakar V. Nayak,Jayakar V. Nayak +45 more
TL;DR: In this article, the authors show that SARS-CoV-2 infection is present in all examined head and neck tissues, with a notable tropism for the nasal cavity and tracheal mucosa.
Journal ArticleDOI
Short-term whole body cigarette smoke exposure induces regional differences in cellular response in the mouse larynx.
Meena Easwaran,Joshua D Martinez,Daniel J. Ramirez,Phillip A. Gall,Elizabeth Erickson-DiRenzo +4 more
TL;DR: In this paper, the authors developed a short-term murine whole body inhalation model to evaluate the first CS-induced cellular responses in the glottic [i.e. vocal fold (VF)] and subglottic regions of the larynx.