P
Pieter C. Dorrestein
Researcher at University of Montana
Publications - 526
Citations - 47251
Pieter C. Dorrestein is an academic researcher from University of Montana. The author has contributed to research in topics: Microbiome & Biology. The author has an hindex of 85, co-authored 470 publications receiving 31806 citations. Previous affiliations of Pieter C. Dorrestein include University of California, Santa Cruz & Northern Arizona University.
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Journal ArticleDOI
The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery.
Jeffrey A. van Santen,Gregoire Jacob,Amrit Leen Singh,Victor Aniebok,Marcy J. Balunas,Derek Bunsko,Fausto Carnevale Neto,Fausto Carnevale Neto,Fausto Carnevale Neto,Laia Castano-Espriu,Chen Chang,Trevor N. Clark,Jessica C. Little,David A. Delgadillo,Pieter C. Dorrestein,Katherine R. Duncan,Joseph M. Egan,Melissa M. Galey,F. P. Jake Haeckl,Alex Hua,Alison H. Hughes,Dasha Iskakova,Aswad S Khadilkar,Jung-Ho Lee,Sanghoon Lee,Nicole LeGrow,Dennis Y. Liu,Jocelyn Macho,Catherine McCaughey,Marnix H. Medema,Ram P. Neupane,Timothy J. O’Donnell,Jasmine S. Paula,Laura M. Sanchez,Anam F. Shaikh,Sylvia Soldatou,Barbara R. Terlouw,Tuan Anh Tran,Tuan Anh Tran,Mercia C. Valentine,Justin J. J. van der Hooft,Duy A. Vo,Mingxun Wang,Darryl Wilson,Katherine E. Zink,Roger G. Linington +45 more
TL;DR: The Natural Products Atlas is designed as a community-supported resource to provide a central repository for known natural product structures from microorganisms and is the first comprehensive, open access resource of this type.
Journal ArticleDOI
The intestinal metabolome: an intersection between microbiota and host.
Luke K. Ursell,Henry J. Haiser,Will Van Treuren,Neha Garg,Lavanya Reddivari,Jairam Vanamala,Pieter C. Dorrestein,Peter J. Turnbaugh,Rob Knight,Rob Knight +9 more
TL;DR: How the microbiota determines levels of specific metabolites, how the metabolite profile develops in infants, and prospects for assessing a person's physiological state based on their microbes and/or metabolites are reviewed.
Journal ArticleDOI
MS/MS networking guided analysis of molecule and gene cluster families
Don D. Nguyen,Cheng-Hsuan Wu,Wilna J. Moree,Anne Lamsa,Marnix H. Medema,X. Zhao,Ronnie G. Gavilan,Marystella Aparicio,Librada A. Atencio,Chanaye Jackson,Javier Ballesteros,Joel Sanchez,Jeramie D. Watrous,Vanessa V. Phelan,Corine van de Wiel,Roland D. Kersten,Samina Mehnaz,René De Mot,Elizabeth A. Shank,Pep Charusanti,Harish Nagarajan,Brendan M. Duggan,Bradley S. Moore,Nuno Bandeira,Bernhard O. Palsson,Kit Pogliano,Marcelino Gutiérrez,Pieter C. Dorrestein +27 more
TL;DR: This paper matched the molecular families of peptide natural products produced by 42 bacilli and 18 pseudomonads through the generation of amino acid sequence tags from MS/MS data of specific clusters found in the MS/ MS network, providing the ability to link particular molecules with the genes that produced them.
Journal ArticleDOI
Molecular Networking As a Drug Discovery, Drug Metabolism, and Precision Medicine Strategy
Robert A. Quinn,Louis-Félix Nothias,Oliver B. Vining,Michael J. Meehan,Eduardo Esquenazi,Pieter C. Dorrestein,Pieter C. Dorrestein +6 more
TL;DR: The principles behind molecular networking are highlighted and its use for the discovery of therapeutic leads, monitoring drug metabolism, clinical diagnostics, and emerging applications in precision medicine are highlighted.
Journal ArticleDOI
Interkingdom metabolic transformations captured by microbial imaging mass spectrometry
Wilna J. Moree,Vanessa V. Phelan,Cheng-Hsuan Wu,Nuno Bandeira,Dale S. Cornett,Brendan M. Duggan,Pieter C. Dorrestein +6 more
TL;DR: This work highlights the capabilities of MALDI-IMS and MS/MS network analysis to study interkingdom interactions and provides insight into the complex nature of polymicrobial metabolic exchange and biotransformations.