J
Joseph M. Egan
Researcher at University of North Carolina at Greensboro
Publications - 12
Citations - 589
Joseph M. Egan is an academic researcher from University of North Carolina at Greensboro. The author has contributed to research in topics: Efflux & Goldenseal. The author has an hindex of 7, co-authored 11 publications receiving 373 citations. Previous affiliations of Joseph M. Egan include Simon Fraser University.
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Journal ArticleDOI
The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery.
Jeffrey A. van Santen,Gregoire Jacob,Amrit Leen Singh,Victor Aniebok,Marcy J. Balunas,Derek Bunsko,Fausto Carnevale Neto,Fausto Carnevale Neto,Fausto Carnevale Neto,Laia Castano-Espriu,Chen Chang,Trevor N. Clark,Jessica C. Little,David A. Delgadillo,Pieter C. Dorrestein,Katherine R. Duncan,Joseph M. Egan,Melissa M. Galey,F. P. Jake Haeckl,Alex Hua,Alison H. Hughes,Dasha Iskakova,Aswad S Khadilkar,Jung-Ho Lee,Sanghoon Lee,Nicole LeGrow,Dennis Y. Liu,Jocelyn Macho,Catherine McCaughey,Marnix H. Medema,Ram P. Neupane,Timothy J. O’Donnell,Jasmine S. Paula,Laura M. Sanchez,Anam F. Shaikh,Sylvia Soldatou,Barbara R. Terlouw,Tuan Anh Tran,Tuan Anh Tran,Mercia C. Valentine,Justin J. J. van der Hooft,Duy A. Vo,Mingxun Wang,Darryl Wilson,Katherine E. Zink,Roger G. Linington +45 more
TL;DR: The Natural Products Atlas is designed as a community-supported resource to provide a central repository for known natural product structures from microorganisms and is the first comprehensive, open access resource of this type.
Journal ArticleDOI
Biochemometrics for Natural Products Research: Comparison of Data Analysis Approaches and Application to Identification of Bioactive Compounds
Joshua J. Kellogg,Daniel A. Todd,Joseph M. Egan,Huzefa A. Raja,Nicholas H. Oberlies,Olav M. Kvalheim,Nadja B. Cech +6 more
TL;DR: The potential of biochemometrics coupled with bioassay-guided fractionation to identify bioactive mixture components is demonstrated, demonstrating the ability to integrate multiple stages of fractionation and bioassays data into a single analysis.
Journal ArticleDOI
The Value of Universally Available Raw NMR Data for Transparency, Reproducibility, and Integrity in Natural Product Research
James B. McAlpine,Shao-Nong Chen,Andrei G. Kutateladze,John B. MacMillan,Giovanni Appendino,Andersson Barison,Mehdi A. Beniddir,Maique W. Biavatti,Stefan Bluml,Asmaa Boufridi,Mark S. Butler,Robert J. Capon,Young Hae Choi,David Coppage,Phillip Crews,Michael T. Crimmins,Marie Csete,Pradeep Dewapriya,Joseph M. Egan,Mary J. Garson,Grégory Genta-Jouve,William H. Gerwick,William H. Gerwick,Harald Gross,Mary Kay Harper,Precilia Hermanto,James M. Hook,Luke Hunter,Damien Jeannerat,Nai Yun Ji,Tyler A. Johnson,David G. I. Kingston,Hiroyuki Koshino,Hsiau Wei Lee,Guy Lewin,Jie Li,Roger G. Linington,Miaomiao Liu,Kerry L. McPhail,Tadeusz F. Molinski,Bradley S. Moore,Bradley S. Moore,Joo-Won Nam,Ram P. Neupane,Matthias Niemitz,Jean-Marc Nuzillard,Nicholas H. Oberlies,Fernanda Maria Marins Ocampos,Guohui Pan,Ronald J. Quinn,D. Sai Reddy,Jean-Hugues Renault,José Rivera-Chávez,Wolfgang Robien,Carla M. Saunders,Thomas J. Schmidt,Christoph Seger,Ben Shen,Christoph Steinbeck,Hermann Stuppner,Sonja Sturm,Orazio Taglialatela-Scafati,Dean J. Tantillo,Robert Verpoorte,Bin Gui Wang,Craig M. Williams,Philip G. Williams,Julien Wist,Jian Min Yue,Chen Zhang,Zhengren Xu,Charlotte Simmler,David C. Lankin,Jonathan Bisson,Guido F. Pauli +74 more
TL;DR: In this article, the authors present a comprehensive review of the scientific value of disseminating raw nuclear magnetic resonance (NMR) data, independently of, and in parallel with, classical publishing outlets.
Journal ArticleDOI
A Mass Spectrometry-Based Assay for Improved Quantitative Measurements of Efflux Pump Inhibition
Adam R. Brown,Keivan A. Ettefagh,Daniel A. Todd,Patrick S. Cole,Joseph M. Egan,Daniel H. Foil,Tyler N. Graf,Bryan D. Schindler,Glenn W. Kaatz,Nadja B. Cech +9 more
TL;DR: A new mass spectrometry-based method was developed for the quantitative measurement of bacterial efflux pump inhibition and could be useful in future screening efforts to identify efflux pumps inhibitors, particularly in situations where optical interference precludes the application of methods that rely on fluorescence.
Journal ArticleDOI
The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research (vol 36, pg 35, 2018)
James B. McAlpine,Shao-Nong Chen,Andrei G. Kutateladze,John B. MacMillan,Giovanni Appendino,Andersson Barison,Mehdi A. Beniddir,Maique W. Biavatti,Stefan Bluml,Asmaa Boufridi,Mark S. Butler,Robert J. Capon,Young Hae Choi,David Coppage,Phillip Crews,Michael T. Crimmins,Marie Csete,Pradeep Dewapriya,Joseph M. Egan,Mary J. Garson,Grégory Genta-Jouve,William H. Gerwick,Harald Gross,Mary Kay Harper,Precilia Hermanto,James M. Hook,Luke Hunter,Damien Jeannerat,Nai Yun Ji,Tyler A. Johnson,David G. I. Kingston,Hiroyuki Koshino,Hsiau-Wei Lee,Guy Lewin,Jie Li,Roger G. Linington,Miaomiao Liu,Kerry L. McPhail,Tadeusz F. Molinski,Bradley S. Moore,Joo-Won Nam,Ram P. Neupane,Matthias Niemitz,Jean-Marc Nuzillard,Nicholas H. Oberlies,Fernanda Maria Marins Ocampos,Guohui Pan,Ronald J. Quinn,D. Sai Reddy,Jean-Hugues Renault,José Rivera-Chávez,Wolfgang Robien,Carla M. Saunders,Thomas J. Schmidt,Christoph Seger,Ben Shen,Christoph Steinbeck,Hermann Stuppner,Sonja Sturm,Orazio Taglialatela-Scafati,Dean J. Tantillo,Robert Verpoorte,Bin Gui Wang,Craig M. Williams,Philip G. Williams,Julien Wist,Jian-Min Yue,Chen Zhang,Zhengren Xu,Charlotte Simmler,David C. Lankin,Jonathan Bisson,Guido F. Pauli +72 more
TL;DR: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research is supported by a literature review and meta-analysis.