G
Gregory A. Shanower
Researcher at Rutgers University
Publications - 10
Citations - 2648
Gregory A. Shanower is an academic researcher from Rutgers University. The author has contributed to research in topics: Chromatin & Histone. The author has an hindex of 9, co-authored 10 publications receiving 2503 citations. Previous affiliations of Gregory A. Shanower include Wright State University & Princeton University.
Papers
More filters
Journal ArticleDOI
Comprehensive analysis of the chromatin landscape in Drosophila melanogaster
Peter V. Kharchenko,Artyom A. Alekseyenko,Artyom A. Alekseyenko,Yuri B. Schwartz,Aki Minoda,Nicole C. Riddle,Jason Ernst,Jason Ernst,Peter J. Sabo,Erica Larschan,Erica Larschan,Erica Larschan,Andrey A. Gorchakov,Andrey A. Gorchakov,Tingting Gu,Daniela Linder-Basso,Annette Plachetka,Annette Plachetka,Gregory A. Shanower,Michael Y. Tolstorukov,Michael Y. Tolstorukov,Lovelace J. Luquette,Ruibin Xi,Youngsook L. Jung,Youngsook L. Jung,Richard W. Park,Richard W. Park,Eric P. Bishop,Eric P. Bishop,Theresa K. Canfield,Richard Sandstrom,Robert E. Thurman,David M. MacAlpine,John A. Stamatoyannopoulos,Manolis Kellis,Manolis Kellis,Sarah C. R. Elgin,Mitzi I. Kuroda,Mitzi I. Kuroda,Vincenzo Pirrotta,Gary H. Karpen,Peter J. Park,Peter J. Park,Peter J. Park +43 more
TL;DR: In this article, the authors present a genome-wide chromatin landscape for Drosophila melanogaster based on eighteen histone modifications, summarized by nine prevalent combinatorial patterns.
Journal Article
Comprehensive analysis of the chromatin landscape in Drosophila melanogaster
Peter V. Kharchenko,Artyom A. Alekseyenko,Artyom A. Alekseyenko,Yuri B. Schwartz,Aki Minoda,Nicole C. Riddle,Jason Ernst,Jason Ernst,Peter J. Sabo,Erica Larschan,Erica Larschan,Erica Larschan,Andrey A. Gorchakov,Andrey A. Gorchakov,Tingting Gu,Daniela Linder-Basso,Annette Plachetka,Annette Plachetka,Gregory A. Shanower,Michael Y. Tolstorukov,Michael Y. Tolstorukov,Lovelace J. Luquette,Ruibin Xi,Youngsook L. Jung,Youngsook L. Jung,Richard W. Park,Richard W. Park,Eric P. Bishop,Eric P. Bishop,Theresa K. Canfield,Richard Sandstrom,Robert E. Thurman,David M. MacAlpine,John A. Stamatoyannopoulos,Manolis Kellis,Manolis Kellis,Sarah C. R. Elgin,Mitzi I. Kuroda,Mitzi I. Kuroda,Vincenzo Pirrotta,Gary H. Karpen,Peter J. Park,Peter J. Park,Peter J. Park +43 more
TL;DR: It is found that active genes display distinct chromatin signatures that are correlated with disparate gene lengths, exon patterns, regulatory functions and genomic contexts, and a diversity of signatures among Polycomb targets that include a subset with paused polymerase.
Journal ArticleDOI
An assessment of histone-modification antibody quality
Thea A. Egelhofer,Aki Minoda,Aki Minoda,Sarit Klugman,Sarit Klugman,Kyungjoon Lee,P. Kolasinska-Zwierz,Artyom A. Alekseyenko,Ming Sin Cheung,Daniel S. Day,Sarah Gadel,Andrey A. Gorchakov,Tingting Gu,Peter V. Kharchenko,Samantha Kuan,Samantha Kuan,Isabel J. Latorre,Daniela Linder-Basso,Ying Luu,Ying Luu,Que-Minh Ngo,Que-Minh Ngo,Marc D. Perry,Andreas Rechtsteiner,Nicole C. Riddle,Yuri B. Schwartz,Gregory A. Shanower,A. Vielle,Julie Ahringer,Sarah C. R. Elgin,Mitzi I. Kuroda,Vincenzo Pirrotta,Bing Ren,Bing Ren,Susan Strome,Peter J. Park,Gary H. Karpen,Gary H. Karpen,R. David Hawkins,R. David Hawkins,Jason D. Lieb +40 more
TL;DR: The specificity and utility of histone-modification antibodies raised against 57 different histone modifications in Drosophila melanogaster, Caenorhabditis elegans and human cells are tested.
Journal ArticleDOI
Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin
Nicole C. Riddle,Aki Minoda,Peter V. Kharchenko,Artyom A. Alekseyenko,Yuri B. Schwartz,Yuri B. Schwartz,Michael Y. Tolstorukov,Andrey A. Gorchakov,Jacob D. Jaffe,Cameron Kennedy,Daniela Linder-Basso,Sally E. Peach,Gregory A. Shanower,Haiyan Zheng,Mitzi I. Kuroda,Vincenzo Pirrotta,Peter J. Park,Sarah C. R. Elgin,Gary H. Karpen +18 more
TL;DR: In this paper, the composition and organization of Drosophila melanogaster heterochromatin in different cell types using ChIP-array analysis of histone modifications and chromosomal proteins.
Journal ArticleDOI
Nature and function of insulator protein binding sites in the Drosophila genome
Yuri B. Schwartz,Yuri B. Schwartz,Daniela Linder-Basso,Peter V. Kharchenko,Michael Y. Tolstorukov,Maria Kim,Hua-Bing Li,Andrey A. Gorchakov,Andrey A. Gorchakov,Aki Minoda,Gregory A. Shanower,Artyom A. Alekseyenko,Nicole C. Riddle,Youngsook L. Jung,Tingting Gu,Annette Plachetka,Sarah C. R. Elgin,Mitzi I. Kuroda,Peter J. Park,Mikhail Savitsky,Gary H. Karpen,Vincenzo Pirrotta +21 more
TL;DR: Functional characterization of different classes of binding sites indicates that only a small fraction act as robust insulators in standard enhancer-blocking assays, and suggests that insulators are reserved for specific regulation of selected genes.