R
Rafal Pawlinski
Researcher at University of North Carolina at Chapel Hill
Publications - 119
Citations - 7414
Rafal Pawlinski is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Tissue factor & Inflammation. The author has an hindex of 37, co-authored 112 publications receiving 6482 citations. Previous affiliations of Rafal Pawlinski include Scripps Research Institute & Jagiellonian University.
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Journal ArticleDOI
Tissue factor activity is increased in neutrophils from JAK2 V617F-mutated essential thrombocythemia and polycythemia vera patients.
Brandi Reeves,Soo Jin Kim,Jihyun Song,Kathryn Wilson,Michael W. Henderson,Nigel S. Key,Rafal Pawlinski,Josef T. Prchal,Josef T. Prchal +8 more
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Factor XII contributes to thrombotic complications and vaso-occlusion in sickle cell disease.
Erica M. Sparkenbaugh,Michael W. Henderson,Megan D Miller-Awe,Christina M. Abrams,Anton Ilich,Fatima Trebak,Nirupama Ramadas,Shantel Vital,Dillon Bohinc,Kara L. Bane,Chunsheng Chen,Margi Patel,Michael Wallisch,Thomas Renné,Andras Gruber,Brian C. Cooley,David Gailani,Malgorzata Kasztan,Gregory M. Vercellotti,John D. Belcher,Felicity N. E. Gavins,Evi X. Stavrou,Nigel S. Key,Rafal Pawlinski +23 more
TL;DR: In this paper , the authors investigated whether Coagulation Factor XII (FXII) contributes to the prothrombotic and inflammatory complications associated with SCD, and they found that SCD patients exhibit increased circulating biomarkers of FXII activation that are associated with increased activation of the contact pathway.
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Platelet HMGB1: the venous clot coordinator.
TL;DR: It is reported that the platelet-derived high-mobility group box 1 protein (HMGB1) orchestrates an inflammation-induced venous thrombosis.
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Using heparan sulfate octadecasaccharide (18-mer) as a multi-target agent to protect against sepsis
Yi En Liao,Yongmei Xu,Katelyn Arnold,Fuming Zhang,Jine Li,Rani S. Sellers,Chaoying Yin,Vijayakanth Pagadala,Anna Marie Inman,Robert J. Linhardt,Ding Xu,Rafal Pawlinski,Jian Liu +12 more
TL;DR: In this article , an octadecasaccharide (18-mer) was shown to inhibit the inflammatory responses of the host animals to achieve protection against sepsis in human clinical trials.
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An inhibitory effect of interferon gamma on the injury-induced astrocyte proliferation in the postmitotic rat brain.
TL;DR: In this paper, the influence of interferon gamma (IFNγ) on astrocytes proliferating in response to unilateral injury of the cerebral hemisphere was investigated in 30-day-old rats.