R
Rafal Pawlinski
Researcher at University of North Carolina at Chapel Hill
Publications - 119
Citations - 7414
Rafal Pawlinski is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Tissue factor & Inflammation. The author has an hindex of 37, co-authored 112 publications receiving 6482 citations. Previous affiliations of Rafal Pawlinski include Scripps Research Institute & Jagiellonian University.
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Journal Article
Intralesional injection of interferon gamma affects reactive proliferation of astrocytes in the neonatal rat brain. A preliminary study of the age-dependent effect
TL;DR: Changes appear to indicate a non-linear relation between the intensity of reactive behaviour of astrocytes and the amount of IFN gamma injected into the lesion area.
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The Synthetic Pentasaccharide, Fondaparinux, Reduces Inflammation and Neutrophil Accumulation in Kidney Ischemia-Reperfusion Injury.
Gernot Schabbauer,Rolf Dario Frank,Todd Holscher,Yuichiro Sato,Michael Tencati,Rafal Pawlinski,Nigel Mackman +6 more
TL;DR: The data indicate that fondaparinux has both anticoagulant and anti-inflammatory activity reducing fibrin deposition and blocking the binding of inflammatory cells to activated endothelium.
Journal ArticleDOI
Inhibit the calpain to climb the mountain.
TL;DR: The authors observed the splicing of TF pre–messenger RNA (pre-mRNA) and increased levels of TF protein in platelets isolated from hypoxic rats, and the calpain-dependent release of procoagulant microparticles from platelets has been previously described.
Journal ArticleDOI
Cell biology and signaling
Maya Agarwal,Ryan T. Nitta,Sinisa Dovat,Gordon Li,Hideyuki Arita,Yoshitaka Narita,Shintaro Fukushima,Kensuke Tateishi,Yuko Matsushita,Akihiko Yoshida,Yasuji Miyakita,Makoto Ohno,V. Peter Collins,Nobutaka Kawahara,Soichiro Shibui,Koichi Ichimura,Suzana Assad Kahn,Sharareh Gholamin,Marie-Pierre Junier,Hervé Chneiweiss,Irving L. Weissman,Siddhartha Mitra,Samuel H. Cheshier,Tony Avril,Abderrahmane Hamlat,Pierre-Jean Le Reste,Jean Mosser,Véronique Quillien,Cristina Carrato,Ana M. Muñoz-Mármol,Laia Serrano,Lara Pijuán,Cristina Hostalot,Saand lvador Villa,Aurelio Ariza,O. Etxaniz,Carmen Balana,Etty Tika Benveniste,Ying Zheng,Braden C. McFarland,Denis Drygin,Susan L. Bellis,Markus Bredel,Daniela Lötsch,Claudia Engelmaier,Sigrid Allerstorfer,Michael Grusch,Josef Pichler,Serge Weis,Johannes A. Hainfellner,Christine Marosi,Sabine Spiegl-Kreinecker,Walter Berger,Agnieszka Bronisz,Michał Nowicki,Yan Wang,Khairul I. Ansari,E. Antonio Chiocca,Jakub Godlewski,Kristine Brown,Madan M. Kwatra,Timothy T. Bui,Shan Zhu,David Kozono,Jie Li,Deepa Kushwaha,Bob S. Carter,Clark C. Chen,Jessica Schulte,Maya Srikanth,Sunit Das,Jianing Zhang,Justin D. Lathia,Lihui Yin,Jeremy N. Rich,Eric Olson,Jack Kessler,Anjen Chenn,Allison Cherry,Brian Haas,Yi Hsing Lin,Shao-En Ong,Nephi Stella,Christopher P. Cifarelli,Robert J. Griffin,Damin Cong,Damin Cong,Wen Zhu,Yejie Shi,Paul A. Clark,John S. Kuo,Shaoshan Hu,Dandan Sun,Markus Bookland,Nune Darbinian,Abhinav Dey,Mélanie Robitaille,Marc Remke,Damien Faury,Caroline Maier,Anshu Malhotra,Nada Jabado,Michael D. Taylor,Stephane Angers,Anna Kenney,Xiuhai Ren,Hong Zhou,Mathew Schur,Abinav Baweja,Mohan Singh,Anat Erdreich-Epstein,Anat Erdreich-Epstein,Jun Fu,Dimpy Koul,Jun Yao,Norihiko Saito,Siyuan Zheng,Roel G.W. Verhaak,Zhimin Lu,W. K. Alfred Yung,German G. Gomez,Stefano Volinia,Carlo M. Croce,Cameron Brennan,Webster K. Cavenee,Webster K. Cavenee,Frank B. Furnari,Frank B. Furnari,Sandra Gomez Lopez,Dian Qu,Claudia Petritsch,Marisol Gonzalez-Huarriz,Guillermo Aldave,Datta Ravi,Angel Rubio,Ricardo Díez-Valle,Miguel Marigil,Patricia Jauregi,Beatriz Vera,Arlet M. Acanda de la Rocha,Sonia Tejada-Solís,Marta M. Alonso,Udhayakumar Gopal,Jennifer Isaacs,Mariella Gruber-Olipitz,Mariella Gruber-Olipitz,Sukriti K. Dabral,Sukriti K. Dabral,Shakti Ramkissoon,Andrew L. Kung,Andrew L. Kung,Ekaterina Pak,Ekaterina Pak,Jarom Chung,Jarom Chung,Matthew A. Theisen,Yanping Sun,Valerie Monrose,Yoko Franchetti,Yu Sun,David S. Shulman,David S. Shulman,Navid Redjal,Barbara Tabak,Rameen Beroukhim,Jean J. Zhao,Silvia Buonamici,Keith L. Ligon,Joseph Kelleher,Rosalind A. Segal,Rosalind A. Segal,Dave Canton,Philippe Diaz,John D. Scott,Keijiro Hara,Teruyoshi Kageji,Yoshifumi Mizobuchi,Keiko T. Kitazato,Toshiyuki Okazaki,Toshitaka Fujihara,Kohei Nakajima,Hideo Mure,Kazuyuki Kuwayama,Tomoyo Hara,Shinji Nagahiro,Lisa J Hill,Hannah Botfield,Kismet Hossain-Ibrahim,Ann Logan,Garth Cruickshank,Yinxing Liu,Misty R. Gilbert,Natasha Kyprianou,Vivek M. Rangnekar,Craig Horbinski,Yuanjie Hu,Chris Vo,Zhenzhi Li,Chao Ke,Chao Ke,Ning Ru,Kenneth R. Hess,Mark E. Linskey,Yi-and Hong Zhou,Feng Hu,Katyayni Vinnakota,Susanne A. Wolf,Helmut Kettenmann,Pauline Jackson,Jon D. Larson,Jon D. Larson,Dominic A. Beckmann,Branden S. Moriarity,David A. Largaespada,Shahrzad Jalali,Sameer Agnihotri,Sanjay K. Singh,Kelly Burrell,Sidney Croul,Gelareh Zadeh,Shin Hyuk Kang,Mi Ok Yu,Na-Hyun Song,Kyung-Jae Park,Sung Gil Chi,Yong-Gu Chung,Sung Kwon Kim,Jin Wook Kim,Ji Young Kim,Ja Eun Kim,Seung Hong Choi,Tae Min Kim,Se-Hoon Lee,Seung-Ki Kim,Sung Hye Park,Il Han Kim,Chul-Kee Park,Hee-Won Jung,Michael Koldobskiy,Ishrat Ahmed,Gary Ho,Adele Snowman,Eric Raabe,Charles Eberhart,Solomon Snyder,Isabel Gugel,Antje Bornemann,Georgios Pantazis,Stephen C. Mack,David Shih,Nesrin Sabha,Marcos Tatagiba,Boris Krischek,Boris Krischek,Alexander Schulte,Katrin Liffers,Annegret Kathagen,Sabine Riethdorf,Manfred Westphal,Katrin Lamszus,Jun Sung Lee,Jiping Xiao,Parita Patel,Jake Schade,Jinhua Wang,Benjamin Deneen,Hae-Ri Song,Lina Leiss,Lina Leiss,Christiane H. Gjerde,Halala Saed,Aminur Mohummad Rahman,Mohammad S. Lellahi,Per Øyvind Enger,Per Øyvind Enger,Richard Leung,Orlando Gil,Liang Lei,Peter Canoll,Stella Sun,Derek Lee,Amy S.W. Ho,Jenny Kan-suen Pu,Xiao-Qin Zhang,Nikki P. Lee,Philip J.r. Dat,Gilberto K.K. Leung,Daniela Loetsch,Elisabeth Steiner,Klaus Holzmann,Christine Pirker,Juraj Hlavaty,Helga Petznek,Balazs Hegedus,Balazs Hegedus,Tamás Garay,Thomas Mohr,Wolfgang Sommergruber,Walter J. Lukiw,Brandon M. Jones,Yuhai Zhao,Surjyadipta Bhattacharjee,Frank Culicchia,Nathalie Magnus,Delphine Garnier,Brian Meehan,Serge McGraw,Maryam Hashemi,Tae Hoon Lee,Chloe Milsom,Noha Gerges,Jacquetta M. Trasler,Rafal Pawlinski,Nigel Mackman,Janusz Rak,Zaynah Maherally,Adam Thorne,Qian An,Qian An,Eugen Barbu,Helen Fillmore,Geoff Pilkington,Sim Ling Tan,Sim Ling Tan,Sophie Tan,Sophie Tan,SunPhil Choi,Chad Potts,David A. Ford,Zaher Nahlé,Anna Marie Kenney,Lisa Matlaf,Sabeena Khan,Alex Zider,Eric Singer,Charles Cobbs,Liliana Soroceanu,Braden C. McFarland,Suk W. Hong,Rajani Rajbhandari,George B. Twitty,G. Kenneth Gray,Hao Yu,Etty N. Benveniste,Susan Nozell,Mutsuko Minata,Sunghak Kim,Ping Mao,Jothi Kaushal,Ichiro Nakano,Takashi Mizowaki,Takashi Sasayama,Kazuhiro Tanaka,Katsu Mizukawa,Masamitsu Nishihara,Satoshi Nakamizo,Hirotomo Tanaka,Masaaki Kohta,Kohkichi Hosoda,Eiji Kohmura,Sylvia Moeckel,Katharina Meyer,Petra Leukel,Ulrich Bogdahn,Markus J. Riehmenschneider,Anja-Katrin Bosserhoff,Rainer Spang,Peter Hau,Akitake Mukasa,Akira Watanabe,Akira Watanabe,Hideki Ogiwara,Nobuhito Saito,Hiroyuki Aburatani,Joydeep Mukherjee,Shigeo Obha,Wendy L. See,Russell O. Pieper,Yoshihumi Mizobuchi,Ryotaro Otsuka,David Kung,Tanvi Sinha,Gordon Meares,Susan Nozell,Martina Ott,Martina Ott,Ulrike M. Litzenburger,Ulrike M. Litzenburger,Katharina J. Rauschenbach,Katharina J. Rauschenbach,Lukas Bunse,Lukas Bunse,Stefan Pusch,Stefan Pusch,Katharina Ochs,Katharina Ochs,Felix Sahm,Felix Sahm,Christiane A. Opitz,Christiane A. Opitz,Andreas von Deimling,Andreas von Deimling,Wolfgang Wick,Wolfgang Wick,Michael Platten,Michael Platten,Pierpaolo Peruzzi,Renee Read,Renee Read,Tim R. Fenton,Tim R. Fenton,Jill Wykosky,Jill Wykosky,Scott R. VandenBerg,Ivan Babic,Ivan Babic,Akio Iwanami,Huijun Yang,Huijun Yang,Paul S. Mischel,Paul S. Mischel,John B. Thomas,Michael W. Ronellenfitsch,Anna L. Thiepold,Patrick N. Harter,Michel Mittelbronn,Joachim P. Steinbach,Yulia Rybakova,Amanda L. Kalen,Ehab H. Sarsour,Prabhat C. Goswami,Joachim Silber,Girish Harinath,Beatriz Aldaz,Armida W.M. Fabius,Sevin Turcan,Timothy A. Chan,Jason T. Huse,Adam M. Sonabend,Mukesh Bansal,Paolo Guarnieri,Craig R. Soderquist,Jonathan Yun,Benjamin C. Kennedy,Julia Sisti,Samuel S. Bruce,Rachel Bruce,Reena Shakya,Thomas Ludwig,Steven S. Rosenfeld,Peter A. Sims,Jeffrey N. Bruce,Andrea Califano,Marie-Thérése Stockhausen,Karina Kristoffersen,Louise Stobbe Olsen,Hans Skovgaard Poulsen,Brett W. Stringer,Bryan W. Day,Guy Barry,Michael Piper,Paul R. Jamieson,Kathleen S. Ensbey,Zara C. Bruce,Linda J. Richards,Andrew W. Boyd,Andrew W. Boyd,Alexandra Sufit,Tamara M. Burleson,John P Le,Amy K. Keating,Amy K. Keating,Terje Sundstrøm,Terje Sundstrøm,Jobin K. Varughese,Patrick Harter,Lars Prestegarden,Lars Prestegarden,Kjell Petersen,Francisco Azuaje,Clifford G. Tepper,Elizabeth S. Ingham,Lisa Even,Sarah Johnson,Kai Ove Skaftnesmo,Morten Lund-Johansen,Morten Lund-Johansen,Rolf Bjerkvig,Katherine W. Ferrara,Frits Thorsen,Hideo Takeshima,Shinji Yamashita,Kiyotaka Yokogami,Souhei Mizuguchi,Hideo Nakamura,Jun Ichi Kuratsu,Tsuyoshi Fukushima,Kazuhiro Morishita,Yujie Tang,Dedeepya Vaka,S. Chen,Anitha Ponnuswami,Yoon Jae Cho,Michelle Monje,Taishi Nakamura,Daniel P. Cahill,Katja Tiemann,Håkan Hedman,Simone P. Niclou,Marco Timmer,Robin Tjiong,Gabriele Röhn,Roland Goldbrunner,Pantelis Stavrinou,Moritz Perrech,Mari Tokita,Svetlana Mikheev,Drew Sellers,Andrei Mikheev,Yoshito Kosai,Robert C. Rostomily,Isabel Tritschler,Katharina Seystahl,Judith Johanna Schroeder,Michael Weller,Anna Wade,Aaron E Robinson,Joanna J. Phillips,Yuanying Gong,Yufang Ma,Zhixiang Cheng,Reid Thompson,Jialiang Wang,Q-W Fan,C Cheng,WC Gustafson,E Charron,P Zipper,Robyn A. Wong,Josephine Chen,Jasmine Lau,C Knobbe-Thosen,M Weller,N Jura,Guido Reifenberger,Kevan M. Shokat,William A. Weiss,Shaofang Wu,Jingjing Hu,Tiffany E. Taylor,Genaro R. Villa,Paul S. Mischel,Paul S. Mischel,Steven L. Gonias,Daisuke Yamashita,Toru Kondo,Hisaaki Takahashi,Akihiro Inoue,Shohei Kohno,Hironobu Harada,Shiro Ohue,Takanori Ohnishi,Peng Li,Jessica M.Y. Ng,Larra W. Yuelling,Fang Du,Tom Curran,Zeng-Jie Yang,Dan Zhu,Robert C. Castellino,Erwin G. Van Meir,Gulnaz Begum,Qiwei Wang,Sung-Sen Yang,Shih-Hua Lin,Kristopher T. Kahle +575 more
TL;DR: The phylogenetically-conserved vertebrate transcription factor, NFIB, is an orchestrator of glial differentiation in the developing mammalian central nervous system and was found to be reduced in glioblastoma (GBM), the commonest and most lethal primary adult brain cancer as mentioned in this paper.
Journal ArticleDOI
Alteration of the Structure and Dynamics of Venous Clot Formation in Human and Murine Sickle Cell Disease
Camille Faes,Anton Ilich,Erica M. Sparkenbaugh,Alisa S. Wolberg,Brian C. Cooley,Kenneth I. Ataga,Nigel S. Key,Rafal Pawlinski +7 more
TL;DR: The data demonstrated that SCD alters the structure and dynamics of venous clot formation and SS mice have increased platelet and fibrin accumulation compared to AA mice in vivo.