Ravi S. Misra

TL;DR: It is demonstrated that the single-cell proteomics platform can be used to differentiate cell types from enzyme-dissociated human lung primary cells and identify specific protein markers for epithelial and mesenchymal cells.

TL;DR: These datasets will facilitate interpretation of risk loci for lung diseases and provide insight into regulatory logic underlying genes implicated in COVID-19 in individual lung cell types across age.

TL;DR: The Lung Gene Expression Analysis (LGEA) web portal is an extended version of LungGENS useful for the analysis, display and interpretation of gene expression patterns obtained from single cells, sorted cell populations and whole lung tissues.

TL;DR: It is shown that systemic immunization with NP readily accelerated clearance of a 2009 pandemic H1N1 influenza virus isolate in an antibody-dependent manner, and the antiviral activity of anti-NP IgG may provide a critically needed component of a universal influenza vaccine.

TL;DR: It is shown that influenza-specific memory T cells are insufficient to protect mice against a lethal challenge with a virulent strain of influenza in the absence of B cells, and vaccines that elicit both memory T Cells and Abs to conserved epitopes of influenza may be an effective defense against a wide range of influenza serotypes.