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Richard J. O'Reilly
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 394
Citations - 19814
Richard J. O'Reilly is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 72, co-authored 369 publications receiving 18242 citations. Previous affiliations of Richard J. O'Reilly include University of Western Ontario & Cornell University.
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Journal ArticleDOI
Infusions of Donor Leukocytes to Treat Epstein-Barr Virus-Associated Lymphoproliferative Disorders after Allogeneic Bone Marrow Transplantation
Esperanza B. Papadopoulos,Marc Ladanyi,David Emanuel,Stephen Mackinnon,Farid Boulad,Matthew H. Carabasi,Hugo Castro-Malaspina,Barrett H. Childs,Alfred P. Gillio,Trudy N. Small,James W. Young,Nancy A. Kernan,Richard J. O'Reilly +12 more
TL;DR: In a small number of patients, infusions of unirradiated donor leukocytes were an effective treatment for EBV-associated lymphoproliferative disease that arose after allogeneic bone marrow transplantation.
Journal ArticleDOI
Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts
David Lyden,Alison Z. Young,David Zagzag,Wei Yan,William L. Gerald,Richard J. O'Reilly,Bernhard L. Bader,Richard O. Hynes,Yuan Zhuang,Katia Manova,Robert Benezra +10 more
TL;DR: Targeted disruption of the dominant negative helix–loop–helix proteins Id1 and Id3 in mice results in premature withdrawal of neuroblasts from the cell cycle and expression of neural-specific differentiation markers, which are required to maintain the timing of neuronal differentiation in the embryo and invasiveness of the vasculature.
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Transplantation Outcomes for Severe Combined Immunodeficiency, 2000–2009
Sung-Yun Pai,Brent R. Logan,Linda M. Griffith,Rebecca H. Buckley,Roberta E. Parrott,Christopher C. Dvorak,Neena Kapoor,Imelda C. Hanson,Alexandra H. Filipovich,Soma Jyonouchi,Kathleen E. Sullivan,Trudy N. Small,Lauri Burroughs,Suzanne Skoda-Smith,Ann E. Haight,Audrey Grizzle,Michael A. Pulsipher,Ka Wah Chan,Ramsay Fuleihan,Elie Haddad,Brett Loechelt,Victor M. Aquino,Alfred P. Gillio,Jeffrey H. Davis,Alan P. Knutsen,Angela R. Smith,Theodore B. Moore,Marlis L. Schroeder,Frederick D. Goldman,James A. Connelly,Matthew H. Porteus,Qun Xiang,William T. Shearer,Thomas A. Fleisher,Donald B. Kohn,Jennifer M. Puck,Luigi D. Notarangelo,Morton J. Cowan,Richard J. O'Reilly +38 more
TL;DR: Transplants from donors other than matched siblings were associated with excellent survival among infants with SCID identified before the onset of infection.
Journal ArticleDOI
Cytomegalovirus Pneumonia after Bone Marrow Transplantation Successfully Treated with the Combination of Ganciclovir and High-Dose Intravenous Immune Globulin
David Emanuel,I Cunningham,Kethy Jules-Elysee,Joel A. Brochstein,Nancy A. Kernan,Joseph Laver,Diane E. Stover,Dorothy A. White,Anna O. S. Fels,Bruce Polsky,Hugo Castro-Malaspina,Joanne Peppard,Patricia Bartus,Ulrich Hämmerling,Richard J. O'Reilly +14 more
TL;DR: Ganciclovir, when combined with high-dose intravenous immune globulin, appears to have significantly altered the outcome of patients with cytomegalovirus pneumonia after allogeneic bone marrow transplantation.
Journal ArticleDOI
Effects of Recombinant Human Granulocyte Colony-Stimulating Factor on Neutropenia in Patients with Congenital Agranulocytosis
Mary Ann Bonilla,Alfred P. Gillio,Mary Ruggeiro,Nancy A. Kernan,Joel A. Brochstein,Miguel R. Abboud,Luca Fumagalli,Martha Vincent,Janice Gabrilove,Karl Welte,Lawrence M. Souza,Richard J. O'Reilly +11 more
TL;DR: Treatment with rhG-CSF can lead to a large increase in the numbers of functional neutrophils in patients with congenital agranulocytosis, and the number of new infectious episodes and the requirement for intravenous antibiotics have decreased.