Richard M. Epand

TL;DR: It is demonstrated that the peptide 3F-2, which has more potent anti-inflammatory activity in vitro when administered intraperitoneally to female apoE null mice for 6 weeks, inhibits atherosclerosis, whereas 3F14 does not, which supports the proposal that the molecular basis for the difference in the biological activities of the two peptides lies with their different interactions with membranes.

TL;DR: In vitro activation of adenylate cyclase by human calcitonin analogues is not always correlated with in vivo hypocalcemic potency.

TL;DR: The results support the emerging model in which one of the roles of gp41 folding into the SHB conformation is to slow down membrane disruption effects induced by early exposed gp41, however, it can further affect membrane morphology once exposed to negatively charged membranes during late stages.

TL;DR: The ganglioside GD1a, which serves as a receptor for Sendai virus, also affects lipid polymorphism as determined by 31P nuclear magnetic resonance, and enhances virus binding to liposomes of all the compositions studied, but leakage rates and fusion rate constants are either unaffected or reduced.

TL;DR: The property of lipid polymorphism can be applied to understand how fundamental intrinsic curvature properties of a membrane alter the physical properties of the membrane bilayer, which will affect the functional characteristics of membrane proteins.