Richard M. Epand

TL;DR: Three antiviral agents inhibited myelin basic protein-induced membrane fusion when present at low concentrations in the membrane when the mechanism by which these agents affect membrane properties was investigated.

TL;DR: The effects of the very long chain fatty acids, arachidic and behenic appears to be similar to those of cholesterol in that they cause a broadening of the phase Transition with a lowering of the transition enthalpy but have little effect on the temperature at which the phase transition occurs.

TL;DR: This work shows the insensitivity of phase segregation to the specific arrangement of the cationic charges in the peptide sequence as well as to their tendency to form different secondary structures and establishes the role of anionic lipid clustering in the presence of zwitterionic lipids in determining antimicrobial selectivity.

TL;DR: A series of C18 and C22 fatty acids, with varying degrees of unsaturation, were tested for their ability to alter the bilayer to hexagonal phase transition temperature of dielaidoylphosphatidylethanolamine mixtures and found that increasing unsaturation of the fatty acid generally increased theirhexagonal phase-forming ability.

TL;DR: A general formula is derived for modeling ITC titration heats in both binding and partitioning systems that allows for the modeling of the classic incorporation or binding protocols, as well as of new protocols assessing the release of solute from previously solute-loaded vesicles upon dilution.